Objectives estimate the prevalence of ototoxic hearing loss in drug-resistant tuberculosis
(DR-TB) patients treated with aminoglycoside antibiotics via a systematic review and meta …

The Comprehensive Resistance Prediction for Tuberculosis: an International Consortium
(CRyPTIC) presents here a data compendium of 12,289 Mycobacterium tuberculosis global …

BACKGROUND: The use of injectable antibiotics to treat multidrug-resistant TB (MDR-TB) is
associated with substantial morbidity due to long-term hearing loss. This systematic review …

Adverse drug events constitute a major challenge for the success of clinical trials. Several
computational strategies have been suggested to estimate the risk of adverse drug events in …

ABSTRACT OBJECTIVE to analyze the temporal trend, identify the factors related and
elaborate a predictive model for unfavorable treatment outcomes for multidrug-resistant …

Mechanosensory hair cells of the inner ears and lateral line of vertebrates display
heightened vulnerability to environmental insult, with damage resulting in hearing and …

Abstract The Comprehensive Resistance Prediction for Tuberculosis: an International
Consortium (CRyPTIC) presents here a compendium of 15,211 Mycobacterium tuberculosis …

Objective: The toxicity associated with the use of kanamycin includes irreversible hearing
loss. There are limited data describing the relationship between hearing loss and kanamycin …

Introduction Aminoglycosides are ototoxic drugs because they have the ability to destroy the
inner ear structures irreversibly. They are used to treat Gram-negative bacterial infections …

Background: People with diabetes mellitus (DM) have a higher risk for drug-resistant
tuberculosis (DR-TB). DR-TB patients with comorbidity of DM were also vulnerable to …