[HTML][HTML] The imprint of salivary secretion in autoimmune disorders and related pathological conditions

KR Bhattarai, R Junjappa, M Handigund, HR Kim… - Autoimmunity …, 2018 - Elsevier
Xerostomia is a state of oral dryness associated with salivary gland dysfunction and is
induced by stress, radiation and chemical therapy, various systemic and autoimmune …

[HTML][HTML] The protective roles of butein on indomethacin induced gastric ulcer in mice

RA Ugan, H Un - The Eurasian Journal of Medicine, 2020 - ncbi.nlm.nih.gov
Objective Butein is a potential agent first isolated from Rhus verniciflua that has medicinal
value in East Asia and has been used in the treatment of gastritis, gastric cancer, and …

[HTML][HTML] Fisetin Attenuates Paracetamol-Induced Hepatotoxicity by Regulating CYP2E1 Enzyme

RA Ugan, E Cadirci, H Un, I Cinar… - Anais da Academia …, 2023 - SciELO Brasil
Paracetamol is one of the drugs that cause hepatic damage. Fisetin has wide
pharmacological effects such as anticancer, antiinflammatory and antioxidant. We aimed to …

The protective effect of Naringenin against ovalbumin-induced allergic rhinitis in rats

A Şahin, MS Sakat, K Kılıç, B Aktan, S Yildirim… - European Archives of …, 2021 - Springer
Background Allergic rhinitis (AR) is a ubiquitous chronic disease with a growing incidence.
We aimed to investigate the protective effect of naringenin against AR induced in rats …

[HTML][HTML] Long-acting anti-inflammatory injectable DEX-Gel with sustained release and self-healing properties regulates TH1/TH2 immune balance for minimally …

L Dai, B Liu, J Lin, Y Jiang, Y Li, Z Yao, S Shen… - Journal of …, 2024 - Springer
Background Allergic rhinitis (AR) is a prevalent immune-related allergic disease, and
corticosteroid nasal sprays serve as the primary treatment for this patient population …

Possible contribution of the neprilysin/ACE pathway to sepsis in mice

RA Ugan, H Un, MA Gurbuz, G Kaya, A Kahramanlar… - Life Sciences, 2020 - Elsevier
Aim Omapatrilat is an antagonist of angiotensin-converting (ACE) and neprilysin-
neuropeptidase (NEP) enzymes. The aim of our study is to show that omapatrilat may have …

The effect of desloratadine on ischemia reperfusion induced oxidative and inflammatory renal injury in rats

H Kocaturk, F Bedir, MS Altay, E Bakan, B Suleyman… - Renal failure, 2020 - Taylor & Francis
Purpose To examine the effect of desloratadine on kidney ischemia-reperfusion (I/R) injury
in albino Wistar male rats using biochemical and histopathological methods. Methods The …

Desloratadine via its anti-inflammatory and antioxidative properties ameliorates TNBS-induced experimental colitis in rats

MA Bhat, S Roy, S Dhaneshwar, S Kumar… - …, 2024 - Taylor & Francis
Background Intestinal mucosal immune cells, notably mast cells, are pivotal in ulcerative
colitis (UC) pathophysiology. Its activation elevates tissue concentrations of histamine …

Histological and biochemical evaluation of the effect of desloratadine drug in parotid gland tissues

IJ Mohammed, ER Sarha, SA Wadee… - Al-Anbar Medical …, 2021 - amj.uoanbar.edu.iq
Background: The functional deterioration of salivary glands is a consequence of a wide
range of factors and significantly interfered with life quality. Desloratadine (an antihistamine) …

Inhibitory effect of Pycnogenol® on airway inflammation in ovalbumin-induced allergic rhinitis

C Günel, B Demirci, A Eryılmaz, M Yılmaz… - Balkan medical …, 2016 - dergipark.org.tr
Background: The supplement Pycnogenol®(PYC) has been used for the treatment of
several chronic diseases including allergic rhinitis (AR). However, the in vivo effects on …