Intratumoral bacteria are an important “accomplice” in tumor development and metastasis

G Wang, X He, Q Wang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
As emerging tumor components, intratumoral bacteria have been found in many solid
tumors. Several studies have demonstrated that different cancer subtypes have distinct …

The impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies

C Guo, L Kong, L Xiao, K Liu, H Cui, Q Xin, X Gu… - Cell & Bioscience, 2023 - Springer
Immunotherapy is one of the fastest developing areas in the field of oncology. Many
immunological treatment strategies for refractory tumors have been approved and marketed …

The impact of antibiotic use on clinical features and survival outcomes of cancer patients treated with immune checkpoint inhibitors

J Zhou, G Huang, WC Wong, D Hu, J Zhu, R Li… - Frontiers in …, 2022 - frontiersin.org
Background Nowadays, immune checkpoint inhibitors (ICIs) have become one of the
essential immunotherapies for cancer patients. However, the impact of antibiotic (ATB) use …

From mucosal infection to successful cancer immunotherapy

AG Goubet, M Rouanne, L Derosa, G Kroemer… - Nature Reviews …, 2023 - nature.com
The clinical management of advanced malignancies of the upper and lower urinary tract has
been revolutionized with the advent of immune checkpoint blockers (ICBs). ICBs reinstate or …

[HTML][HTML] A systematic review and meta-analysis evaluating the impact of antibiotic use on the clinical outcomes of cancer patients treated with immune checkpoint …

A Crespin, C Le Bescop, J de Gunzburg, F Vitry… - Frontiers in …, 2023 - frontiersin.org
Background: Immune checkpoint inhibitors (ICIs) have considerably improved patient
outcomes in various cancer types, but their efficacy remains poorly predictable among …

The role of gut microbiome in immune modulation in metastatic renal cell carcinoma

J Deluce, S Maleki Vareki… - … advances in medical …, 2022 - journals.sagepub.com
Treatment of metastatic renal cell carcinomas (mRCC) has drastically improved since the
advent of immunotherapy with immune checkpoint inhibitors (ICIs), with a significant …

The negative effect of antibiotics on RCC patients with immunotherapy: A systematic review and meta-analysis

Z Luo, S Hao, Y Li, L Cheng, X Zhou… - Frontiers in …, 2022 - frontiersin.org
Background Microbiome dysbiosis is considered a predictive biomarker of clinical response
in renal cell carcinoma (RCC), which can be regulated by antibiotics (ATB). Multiple studies …

Statins and renal cell carcinoma: Antitumor activity and influence on cancer risk and survival

M Santoni, FSM Monteiro, F Massari… - Critical Reviews in …, 2022 - Elsevier
Statins are commonly prescribed to reduce plasma cholesterol levels and risk of
cardiovascular events and mortality. Statin exposure may have cancer-preventive properties …

The gut microbiome, immune check point inhibition and immune-related adverse events in non-small cell lung cancer

P Bredin, J Naidoo - Cancer and Metastasis Reviews, 2022 - Springer
Systemic treatment options for patients with lung cancer have expanded in recent years, with
a number of immunotherapeutic strategies now in our treatment armamentarium. Toxicity of …

[HTML][HTML] Recent advances in primary resistance mechanisms against immune checkpoint inhibitors

YZ Li, HM Zhang - Current Opinion in Oncology, 2022 - journals.lww.com
Recent advances in primary resistance mechanisms against imm... : Current Opinion in
Oncology Recent advances in primary resistance mechanisms against immune checkpoint …