How do Ras isoforms attain oncogenic specificity at the membrane? Oncogenic KRas,
HRas, and NRas (K-Ras, H-Ras, and N-Ras) differentially populate distinct cancers. How …

Neurofibromatosis type 1 (NF1) is a common neurogenetic disorder in which affected
children and adults are predisposed to the development of benign and malignant nervous …

Abstract Neurofibromatosis type 1 (NF1) is a common tumor-predisposition disorder due to
germline mutations in the tumor suppressor gene NF1. A virtually pathognomonic finding of …

It has become clearer that advanced cancer, especially advanced breast cancer, is an
entirely displayed pathological system that is much more complex than previously …

Neurofibromatosis (NF) and tuberous sclerosis complex (TSC) are the two most common
neurocutaneous disorders, both transmitted as autosomal dominant or, in the case of NF …

Cancer initiation and development are increasingly perceived as systems-level phenomena,
where intra-and inter-cellular signaling networks of the ecosystem of cancer and stromal …

Under normal physiologic conditions, cell growth is tightly regulated, thus allowing cells to
respond appropriately to local environmental cues. These cellular responses typically …

31. Andersen LB, Ballester R, Marchuk DA, Chang E, Gutmann DH, Saulino AM, Camonis J,
Wigler M, Collins FS. A conserved alternative splice in the von Recklinghausen …

31. Andersen LB, Ballester R, Marchuk DA, Chang E, Gutmann DH, Saulino AM, Camonis J,
Wigler M, Collins FS. A conserved alternative splice in the von Recklinghausen …