RAD51 and Infertility: A Review and Case-Control Study

JS Sahota, RS Thakur, K Guleria, V Sambyal - Biochemical Genetics, 2024 - Springer
RAD51 is a highly conserved recombinase involved in the strand invasion/exchange of
double-stranded DNA by homologous single-stranded DNA during homologous …

[HTML][HTML] Synaptonemal complex in human biology and disease

E Llano, AM Pendás - Cells, 2023 - mdpi.com
The synaptonemal complex (SC) is a meiosis-specific multiprotein complex that forms
between homologous chromosomes during prophase of meiosis I. Upon assembly, the SC …

Biallelic FANCA variants detected in sisters with isolated premature ovarian insufficiency

EJ Tucker, MF Sharp, A Lokchine, KM Bell… - Clinical …, 2024 - Wiley Online Library
Premature ovarian insufficiency is a common form of female infertility affecting up to 4% of
women and characterised by amenorrhea with elevated gonadotropin before the age of 40 …

Generation of Meiotic Mouse Models Using CRISPR/Cas9 Technology

M Sánchez-Martín, F Sánchez-Sáez, E Llano… - Meiosis: Methods and …, 2024 - Springer
In recent years, targeted genome editing has emerged as an indispensable tool for creating
animal models, facilitating a comprehensive exploration of the molecular mechanisms …

Generación y análisis funcional de dos mutantes murinos de la recombinasa RAD51B

S Luna González - 2023 - gredos.usal.es
La Insuficiencia Ovárica Prematura (POI) implica una alteración en la función ovárica que
causa infertilidad femenina. Recientemente se ha identificado una variante de la …