Comprehensive framework for human health risk assessment of nanopesticides

M Kah, LJ Johnston, RS Kookana, W Bruce… - Nature …, 2021 - nature.com
Nanopesticides are not only in an advanced state of research and development but have
started to appear on the market. Industry and regulatory agencies need a consolidated and …

Experimental and computational nanotoxicology—Complementary approaches for nanomaterial hazard assessment

V Forest - Nanomaterials, 2022 - mdpi.com
The growing development and applications of nanomaterials lead to an increasing release
of these materials in the environment. The adverse effects they may elicit on ecosystems or …

Biological effects of polystyrene micro-and nano-plastics on human intestinal organoid-derived epithelial tissue models without and with M cells

Y Chen, AM Williams, EB Gordon, SE Rudolph… - … , Biology and Medicine, 2023 - Elsevier
Micro-and nano-plastics (MPs and NPs) released from plastics in the environment can enter
the food chain and target the human intestine. However, knowledge about the effects of …

Three-dimensional (3D) liver cell models-a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of …

MA Tutty, D Movia, A Prina-Mello - Drug Delivery and Translational …, 2022 - Springer
Despite the exciting properties and wide-reaching applications of nanobiomaterials (NBMs)
in human health and medicine, their translation from bench to bedside is slow, with a …

Toward Nano‐Specific In Silico NAMs: How to Adjust Nano‐QSAR to the Recent Advancements of Nanotoxicology?

K Ciura, E Moschini, M Stępnik, T Serchi, A Gutleb… - Small, 2024 - Wiley Online Library
The rapid development of engineered nanomaterials (ENMs) causes humans to become
increasingly exposed to them. Therefore, a better understanding of the health impact of …

Emerging role and promise of nanomaterials in organoid research

C Mahapatra, R Lee, MK Paul - Drug Discovery Today, 2022 - Elsevier
Organoids are 3D stem cell-derived self-organization of cells. Organoid bioengineering
helps recreate and tailor their architecture in vitro to generate mini organ-like properties …

Toxicity of transition metal nanoparticles: A review of different experimental models in the gastrointestinal tract

W Hu, C Wang, D Gao, Q Liang - Journal of Applied Toxicology, 2023 - Wiley Online Library
The development of nanotechnology is becoming a major trend nowadays. Nanoparticles
(NPs) have been widely used in fields including food, biomedicine, and cosmetics …

The road to achieving the European commission's chemicals strategy for nanomaterial sustainability—a PATROLS perspective on new approach methodologies

SH Doak, MJD Clift, A Costa, C Delmaar, I Gosens… - Small, 2022 - Wiley Online Library
Abstract The European Green Deal outlines ambitions to build a more sustainable, climate
neutral, and circular economy by 2050. To achieve this, the European Commission has …

Oral bioavailability of bioactive compounds; modulating factors, in vitro analysis methods, and enhancing strategies

C Dima, E Assadpour, A Nechifor, S Dima… - Critical reviews in …, 2024 - Taylor & Francis
Foods are complex biosystems made up of a wide variety of compounds. Some of them,
such as nutrients and bioactive compounds (bioactives), contribute to supporting body …

Impact of nanomaterials on the intestinal mucosal barrier and its application in treating intestinal diseases

W Hao, R Cha, M Wang, P Zhang, X Jiang - Nanoscale Horizons, 2022 - pubs.rsc.org
The intestinal mucosal barrier (IMB) is one of the important barriers to prevent harmful
substances and pathogens from entering the body environment and to maintain intestinal …