Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Most aldosterone-producing adenomas (APAs) have gain-of-function somatic mutations of
ion channels or transporters. However, their frequency in aldosterone-producing cell …

Primary aldosteronism (PA) is the most common form of secondary arterial hypertension,
with a prevalence of approximately 20% in patients with resistant hypertension. In the last …

Aldosterone-producing adenomas with somatic mutations in the KCNJ5 G-protein–coupled
inwardly rectifying potassium channel are a cause of primary aldosteronism. These …

Primary aldosteronism (PA) is the most common form of secondary hypertension, with a
prevalence of 5–10% among patients with hypertension. PA is mainly classified into two …

Tightly controlled Ca2+ influx through voltage-gated Ca2+ channels (Cavs) is indispensable
for proper physiological function. Thus, it is not surprising that Cav loss and/or gain of …

Simple Summary Improvement in the understanding of the development of primary
aldosteronism, the most common cause of endocrine hypertension and mainly caused by …

Aldosterone production is physiologically under the control of circulating potassium and
angiotensin II as well as adrenocorticotropic hormone and other secretagogues such as …

Lack of routine fresh or frozen tissue is a barrier to widespread transcriptomic analysis of
adrenal cortical tumors and an impediment to translational research in endocrinology and …