Initially adopted as a mucolytic about 60 years ago, the cysteine prodrug N-acetylcysteine
(NAC) is the standard of care to treat paracetamol intoxication, and is included on the World …

Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …

Objective. To review the clinical usefulness of N-acetylcysteine (NAC) as treatment or
adjunctive therapy in a number of medical conditions. Use in Tylenol overdose, cystic …

Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

N-Acetylcysteine (NAC), a cysteine prodrug and glutathione (GSH) precursor, has been
used for several decades in clinical therapeutic practices as a mucolytic agent and for the …

The looming severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
long-lasting pandemic of coronavirus disease 2019 (COVID-19) around the globe with …

Many serious infections result from persistent microbial biofilms that do not respond to
conventional antibiotic therapy. Various therapeutic approaches have been developed and …

Asthma is an intractable disease involving the infiltration of inflammatory cells and mucus
plugging. Despite small molecular mucolytics having the ability to break the disulfide bonds …

Recurrent tonsillitis is described as when an individual suffers from several attacks of
tonsillitis per year. Chronic and recurrent tonsillitis both cause repeated occurrences of …

Background Mycobacterium tuberculosis infection is thought to induce oxidative stress. N-
acetyl-cysteine (NAC) is widely used in patients with chronic pulmonary diseases including …