Antigen discovery for the development of cancer immunotherapy
Central to successful cancer immunotherapy is effective T cell antitumor immunity. Multiple
targeted immunotherapies engineered to invigorate T cell-driven antitumor immunity rely on …
targeted immunotherapies engineered to invigorate T cell-driven antitumor immunity rely on …
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
Y Pan, JW Phillips, BD Zhang… - Proceedings of the …, 2023 - National Acad Sciences
Alternative splicing (AS) is prevalent in cancer, generating an extensive but largely
unexplored repertoire of novel immunotherapy targets. We describe I soform peptides from …
unexplored repertoire of novel immunotherapy targets. We describe I soform peptides from …
Defining T cell receptor repertoires using nanovial-based binding and functional screening
The ability to selectively bind to antigenic peptides and secrete effector molecules can
define rare and low-affinity populations of cells with therapeutic potential in emerging T cell …
define rare and low-affinity populations of cells with therapeutic potential in emerging T cell …
[HTML][HTML] Defining T cell receptor repertoires using nanovial-based affinity and functional screening
The ability to selectively bind to antigenic peptides and secrete cytokines can define
populations of cells with therapeutic potential in emerging T cell receptor (TCR) …
populations of cells with therapeutic potential in emerging T cell receptor (TCR) …