Seeking heterocyclic scaffolds as antivirals against dengue virus
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
The multiples fates of the flavivirus RNA genome during pathogenesis
C Mazeaud, W Freppel, L Chatel-Chaix - Frontiers in genetics, 2018 - frontiersin.org
The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow
fever viruses) which constitute important public health concerns worldwide. For several of …
fever viruses) which constitute important public health concerns worldwide. For several of …
Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection
Dengue is considered as a major health issue which causes a number of deaths worldwide
each year; tropical countries are majorly affected by dengue outbreaks. It is considered as …
each year; tropical countries are majorly affected by dengue outbreaks. It is considered as …
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
The recent outbreak of Zika virus (ZIKV) infections in the Americas represents a serious
threat to the global public health. The viral protease that processes viral polyproteins during …
threat to the global public health. The viral protease that processes viral polyproteins during …
Potential role of flavivirus NS2B-NS3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: a review
Flaviviruses are known to cause a variety of diseases in humans in different parts of the
world. There are very limited numbers of antivirals to combat flavivirus infection, and …
world. There are very limited numbers of antivirals to combat flavivirus infection, and …
Molecular insights into the flavivirus replication complex
K Van den Elsen, JP Quek, D Luo - Viruses, 2021 - mdpi.com
Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral
pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever …
pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever …
Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses
MA Martín-Acebes, Á Vázquez-Calvo, JC Saiz - Progress in lipid research, 2016 - Elsevier
Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …
Mechanisms of neuroinvasion and neuropathogenesis by pathologic flaviviruses
L de Vries, AT Harding - Viruses, 2023 - mdpi.com
Flaviviruses are present on every continent and cause significant morbidity and mortality. In
many instances, severe cases of infection with flaviviruses involve the invasion of and …
many instances, severe cases of infection with flaviviruses involve the invasion of and …
Dengue proteins with their role in pathogenesis, and strategies for developing an effective anti‐dengue treatment: A review
Dengue virus is an arbovirus belonging to class Flaviviridae Its clinical manifestation ranges
from asymptomatic to extreme conditions (dengue hemorrhagic fever/dengue shock …
from asymptomatic to extreme conditions (dengue hemorrhagic fever/dengue shock …
Recent developments in recombinant protein–based dengue vaccines
NK Tripathi, A Shrivastava - Frontiers in immunology, 2018 - frontiersin.org
Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …
application as biopharmaceutical products and proven safety record. Various recombinant …