The transition from a fetus to a newborn is the most complex physiologic adaptation that
occurs in human experience. Before medicalization of delivery, the transition had to occur …

Pathophysiology and Management of Persistent Pulmonary Hypertension of the Newborn -
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In 2010, the congenital diaphragmatic hernia (CDH) EURO Consortium published a
standardized neonatal treatment protocol. Five years later, the number of participating …

Pulmonary hypertension remained an unexplained intractable disease with poor prognosis.
In the last 2 decades, however, the diagnosis and treatment methods for this disease …

Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed
circulatory adaptation at birth, seen in about 2/1000 live born infants. While it is mostly seen …

Persistent pulmonary hypertension of the newborn (PPHN) is often secondary to
parenchymal lung disease (such as meconium aspiration syndrome) or lung hypoplasia …

Persistent pulmonary hypertension of the newborn (PPHN) is one of the main causes of
neonatal morbidity and mortality. It is characterized by sustained elevation of pulmonary …

Inhaled nitric oxide (iNO) is approved for use in persistent pulmonary hypertension of the
newborn (PPHN) but does not lead to sustained improvement in oxygenation in one-third of …

Persistent pulmonary hypertension of the newborn (PPHN) is the most common neonatal
form and mostly reversible after a few days with improvement of the underlying pulmonary …

Failure of the normal circulatory adaptation to extrauterine life results in persistent
pulmonary hypertension of the newborn (PPHN). Although this condition is most often …