[HTML][HTML] Determinants for the development of visceral leishmaniasis disease
LI McCall, WW Zhang, G Matlashewski - PLoS pathogens, 2013 - journals.plos.org
Leishmaniasis is a vector-borne neglected tropical disease associated with a spectrum of
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …
[HTML][HTML] Leishmania RNA virus: when the host pays the toll
MA Hartley, C Ronet, H Zangger… - Frontiers in cellular …, 2012 - frontiersin.org
The presence of an RNA virus in a South American subgenus of the Leishmania parasite,
L.(Viannia), was detected several decades ago but its role in leishmanial virulence and …
L.(Viannia), was detected several decades ago but its role in leishmanial virulence and …
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
MB Rogers, JD Hilley, NJ Dickens, J Wilkes… - Genome …, 2011 - genome.cshlp.org
Leishmania parasites cause a spectrum of clinical pathology in humans ranging from
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …
Tissue tropism: Is it an intrinsic characteristic of Leishmania species?
IA Maatallah, K Akarid, M Lemrani - Acta Tropica, 2022 - Elsevier
The genus Leishmania comprises a wide range of species, some of which are pathogenic to
humans and each of which has a different tissue preference, resulting in one of the three …
humans and each of which has a different tissue preference, resulting in one of the three …
Determinants of disease phenotype in trypanosomatid parasites
LI McCall, JH McKerrow - Trends in parasitology, 2014 - cell.com
Trypanosomatid parasites infect over 21 million people worldwide, with a range of disease
phenotypes. Trypanosoma cruzi causes American trypanosomiasis, wherein 30–40% of …
phenotypes. Trypanosoma cruzi causes American trypanosomiasis, wherein 30–40% of …
[HTML][HTML] LeishCyc: a biochemical pathways database for Leishmania major
MA Doyle, JI MacRae, DP De Souza, EC Saunders… - BMC systems …, 2009 - Springer
Background Leishmania spp. are sandfly transmitted protozoan parasites that cause a
spectrum of diseases in more than 12 million people worldwide. Much research is now …
spectrum of diseases in more than 12 million people worldwide. Much research is now …
Identification of novel cell migration‐promoting genes by a functional genetic screen
Here we describe the identification of novel cell migration‐promoting genes based on an
unbiased functional genetic screen in cultured cells. After the introduction of the retroviral …
unbiased functional genetic screen in cultured cells. After the introduction of the retroviral …
[HTML][HTML] Application of next generation sequencing (NGS) for descriptive analysis of 30 genomes of Leishmania infantum isolates in Middle-North Brazil
KSS Carvalho, WJ da Silva Júnior… - Scientific reports, 2020 - nature.com
Visceral leishmaniasis (VL) is a life-threatening disease caused by the protozoa Leishmania
donovani and L. infantum. Likely, L. infantum was introduced in the New World by the Iberic …
donovani and L. infantum. Likely, L. infantum was introduced in the New World by the Iberic …
Intracellular growth and pathogenesis of Leishmania parasites
T Naderer, MJ McConville - Essays in biochemistry, 2011 - portlandpress.com
Parasitic protozoa belonging to the genus Leishmania are the cause of a spectrum of
diseases in humans, as well as chronic long-term infections. These parasites exhibit a …
diseases in humans, as well as chronic long-term infections. These parasites exhibit a …
Screening Leishmania donovani‐specific genes required for visceral infection
WW Zhang, G Matlashewski - Molecular microbiology, 2010 - Wiley Online Library
Comparison of the Leishmania infantum genome with Leishmania braziliensis and
Leishmania major genomes has identified 25 L. infantum species‐specific genes that are …
Leishmania major genomes has identified 25 L. infantum species‐specific genes that are …