Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Screening of H2S donors with a red emission mitochondria-targetable fluorescent probe: Toward discovering a new therapeutic strategy for Parkinson's disease
K Wu, X Wang, L Gong, X Zhai, K Wang, X Qiu… - Biosensors and …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder caused by various factors such as
neuroinflammation, oxidative stress, mitochondrial dysfunction, and neuronal apoptosis …
neuroinflammation, oxidative stress, mitochondrial dysfunction, and neuronal apoptosis …
Structural Modification Endows Small-Molecular SN38 Derivatives with Multifaceted Functions
Y Dai, M Qian, Y Li - Molecules, 2023 - mdpi.com
As a camptothecin derivative, 7-ethyl-10-hydroxycamptothecin (SN38) combats cancer by
inhibiting topoisomerase I. SN38 is one of the most active compounds among camptothecin …
inhibiting topoisomerase I. SN38 is one of the most active compounds among camptothecin …
A hydrogen sulfide and tyrosinase responsive dual-locked fluorophore for selective imaging of melanoma cells
A resorufin-based dual-locked fluorescent probe (RHT) was introduced to image melanoma
cells selectively. RHT was shown to function as an AND molecular logic gate as it emitted a …
cells selectively. RHT was shown to function as an AND molecular logic gate as it emitted a …
Carrier-free nano-prodrugs for minimally invasive cancer therapy
An anticancer nanodrug with few side effects that does not require the use of a nanocarrier,
polyethylene glycol, or other additives has been developed. We have fabricated nano …
polyethylene glycol, or other additives has been developed. We have fabricated nano …
A GSH-activated photosensitizer prodrug for fluorescence imaging-guided chemo-photodynamic therapy
N Xu, F Xu, Y Yao, C Zhang, W Sun, J Du, J Fan… - Sensors and Actuators B …, 2024 - Elsevier
To improve the treatment efficacy of chemotherapy and reduce its side effects, combination
therapy has gained increasing recognition. Nonetheless, it also faces with challenges …
therapy has gained increasing recognition. Nonetheless, it also faces with challenges …
In silico screening of natural products as uPAR inhibitors via multiple structure-based docking and molecular dynamics simulations
Cancer remains one of the most pressing challenges to global healthcare, exerting a
significant impact on patient life expectancy. Cancer metastasis is a critical determinant of …
significant impact on patient life expectancy. Cancer metastasis is a critical determinant of …
Super-resolution Fluorescence Imaging
HH Han, XP He - 2024 - books.rsc.org
Currently, our knowledge of living systems has been extended to the level of individual cells
and molecules, which makes the real-time visualization of subcellular structures and the …
and molecules, which makes the real-time visualization of subcellular structures and the …