Suicidality is a prevalent mental health condition, and managing suicidal patients is one of
the most challenging tasks for health care professionals due to the lack of rapid‐acting …

Background Subanesthetic ketamine has accumulated meta-analytic evidence for rapid
antidepressant effects in treatment-resistant depression (TRD), resulting in both excitement …

Increasing evidence indicates that the pathogenesis of depression is closely linked to
impairments in neuronal synaptic plasticity. Honokiol, a biologically active substance …

Background There is growing evidence to suggest that ginsenoside Rd (GRd) has a
therapeutic effect on depression, but the specific mechanisms behind its activity require …

Background Evidence indicates that vascular endothelial growth factor (VEGF) and matrix
metalloproteinase-9 (MMP-9) influence the pathophysiology of depression. However …

Purpose There is a practical need for the identification of pretreatment clinical and
epidemiological response predictors to repeat ketamine infusions. Response predictors can …

Although we are the experts in treating mental illness, even in the best hands, many of our
patients continue to suffer with long-term distressing and disabling symptoms. As we have …

Clinicians, patients, and families are well aware of the pressing need for more effective
treatments for depression, and this issue of the Journal is focused on new developments in …

CURRICULUM VITAE Page 1 CURRICULUM VITAE Ned H. Kalin, MD Hedberg Professor Chair,
Department of Psychiatry University of Wisconsin School of Medicine and Public Health 6001 …

Introduction: Major depressive disorder (MDD) is a chronic and severe psychiatric disorder,
which is more prevalent in women. Cannabidiol (CBD) is a compound isolated from the …