Genetic variability in cisplatin metabolic pathways and outcome of locally advanced head and neck squamous cell carcinoma patients

AMC Ferreira, JMC Altemani, LT Macedo… - Scientific Reports, 2023 - nature.com
Advanced head and neck squamous cell carcinoma (HNSCC) patients have been treated
with cisplatin (CDDP) chemoradiation, and the variability of treatment effects has been …

Association of Clinical Aspects and Genetic Variants with the Severity of Cisplatin-Induced Ototoxicity in Head and Neck Squamous Cell Carcinoma: A Prospective …

LT Macedo, EFD Costa, BF Carvalho, GJ Lourenço… - Cancers, 2023 - mdpi.com
Simple Summary Cisplatin is recognized as the standard agent for head and neck
squamous cell carcinoma therapy, despite the relevant risk of permanent hearing damage …

A Comparison of Fas-Fas Ligand Mediated Apoptosis with Clinical and Pathological Parameters in Larynx Cancers; Twenty Years After Laryngectomy

AM Bilgili, T Ersözlü - The Turkish Journal of Ear Nose and Throat, 2022 - dergipark.org.tr
Objective: Larynx cancer constitutes 2% of all cancers in adults with 96% of larynx
malignancies being squamous cell carcinoma (SHC). Apoptosis is a cell death mechanism …

[PDF][PDF] MARIA APARECIDA CURSINO

N MATE - repositorio.unicamp.br
Head and neck cancer (HNC) is the set of malignant tumours located in the upper
aerodigestive tract and the therapy is based on radiotherapy concomitant with highdose …