Novel targets to arrest neurodegeneration in several dementing conditions involving
misfolded protein accumulations may be found in the diverse signaling pathways of the …

Neurodegenerative disorders of ageing (NDAs) such as Alzheimer disease, Parkinson
disease, frontotemporal dementia, Huntington disease and amyotrophic lateral sclerosis …

Defective brain hormonal signaling has been associated with Alzheimer's disease (AD), a
disorder characterized by synapse and memory failure. Irisin is an exercise-induced …

Alzheimer's disease (AD) is associated with memory impairment and altered peripheral
metabolism. Mounting evidence indicates that abnormal signaling in a brain-periphery …

Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …

Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by
vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has …

Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

The past 20 years have resulted in unprecedented progress in understanding brain energy
metabolism and its role in health and disease. In this review, which was initiated at the 14th …

Alzheimer's disease (AD) is a devastating neurological disorder that still lacks an effective
treatment, and this has stimulated an intense pursuit of disease‐modifying therapeutics …

The pathogenesis and etiology of diabetes mellitus (DM) and Alzheimer's disease (AD)
share many common cellular and molecular themes. Recently, a growing body of research …