Tumor angiogenesis and vascular normalization: alternative therapeutic targets
C Viallard, B Larrivée - Angiogenesis, 2017 - Springer
Tumor blood vessels are a key target for cancer therapeutic management. Tumor cells
secrete high levels of pro-angiogenic factors which contribute to the creation of an abnormal …
secrete high levels of pro-angiogenic factors which contribute to the creation of an abnormal …
VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity
M Giannotta, M Trani, E Dejana - Developmental cell, 2013 - cell.com
VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
Endothelial cells adopt tissue-specific characteristics to instruct organ development and
regeneration,. This adaptability is lost in cultured adult endothelial cells, which do not …
regeneration,. This adaptability is lost in cultured adult endothelial cells, which do not …
Molecular mechanisms and clinical applications of angiogenesis
P Carmeliet, RK Jain - Nature, 2011 - nature.com
Blood vessels deliver oxygen and nutrients to every part of the body, but also nourish
diseases such as cancer. Over the past decade, our understanding of the molecular …
diseases such as cancer. Over the past decade, our understanding of the molecular …
Basic and therapeutic aspects of angiogenesis
M Potente, H Gerhardt, P Carmeliet - Cell, 2011 - cell.com
Blood vessels form extensive networks that nurture all tissues in the body. Abnormal vessel
growth and function are hallmarks of cancer and ischemic and inflammatory diseases, and …
growth and function are hallmarks of cancer and ischemic and inflammatory diseases, and …
[HTML][HTML] Magnesium alloys for orthopedic applications: A review on the mechanisms driving bone healing
N Wang, S Yang, H Shi, Y Song, H Sun, Q Wang… - Journal of Magnesium …, 2022 - Elsevier
Magnesium (Mg) alloys have attracted a wealth of attention in orthopedic fields for their
superior mechanical properties, degradability, and excellent biocompatibility. Consistently …
superior mechanical properties, degradability, and excellent biocompatibility. Consistently …
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
SP Herbert, DYR Stainier - Nature reviews Molecular cell biology, 2011 - nature.com
The vertebrate vasculature forms an extensive branched network of blood vessels that
supplies tissues with nutrients and oxygen. During vascular development, coordinated …
supplies tissues with nutrients and oxygen. During vascular development, coordinated …
Blood flow forces in shaping the vascular system: a focus on endothelial cell behavior
The endothelium is the cell monolayer that lines the interior of the blood vessels separating
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …
Developmental and pathological angiogenesis
AS Chung, N Ferrara - Annual review of cell and developmental …, 2011 - annualreviews.org
The formation of the vascular network is an intricate and complex process that is an obligate
requirement during vertebrate development. The cardiovascular system is the first organ to …
requirement during vertebrate development. The cardiovascular system is the first organ to …
Targeting the tumour vasculature: insights from physiological angiogenesis
AS Chung, J Lee, N Ferrara - Nature reviews cancer, 2010 - nature.com
The cardiovascular system ensures the delivery of nutrients, oxygen, and blood and immune
cells to all organs and tissues: it is also responsible for the removal of waste metabolites …
cells to all organs and tissues: it is also responsible for the removal of waste metabolites …