Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Biological sex is a fundamental source of phenotypic variability across species. Males and
females have different nutritional needs and exhibit differences in nutrient digestion and …

Characterizing the microbial communities inhabiting specimens is one of the primary
objectives of microbiome studies. A short-read sequencing platform for reading partial …

Background Dairy cows are susceptible to postpartum systemic oxidative stress (OS), which
leads to significant production loss and metabolic disorders. The gut microbiota has been …

Vitamin B-12 deficiency is a major public health problem affecting individuals across the
lifespan, with known hematological, neurological, and obstetric consequences. Emerging …

Methionine is the initiator amino acid for protein synthesis, the methyl source for most
nucleotide, chromatin, and protein methylation, and the carbon backbone for various …

Simple Summary In colorectal cancer cells, reducing the essential amino acid methionine in
the culture medium led to an increase in two markers of response to immune checkpoint …

Dietary restriction of the essential amino acid, methionine, has been shown to induce unique
metabolic protection. The peripheral benefits of methionine restriction (MR) are well …

Age-related gut barrier dysfunction and dysbiosis of the gut microbiome play crucial roles in
human aging. Dietary methionine restriction (MR) has been reported to extend lifespan and …

In recent years, nonalcoholic fatty liver disease (NAFLD) has become the most common liver
disease in the world. As an important model animal, the characteristics of gut microbiota …