Acute pancreatitis (AP) continues to present a substantial burden to patients and healthcare
personnel. Despite its occasionally severe progression and high mortality rate, there is no …

CFTR, the cystic fibrosis (CF) gene-encoded epithelial anion channel, has a prominent role
in driving chloride, bicarbonate and fluid secretion in the ductal cells of the exocrine …

With increased longevity of patients suffering from cystic fibrosis, and widespread lung
transplantation facilities, the sequelae of defective CFTR in other organs than the airways …

Epithelial ion and fluid secretion determine the physiological functions of a broad range of
organs, such as the lung, liver, or pancreas. The molecular mechanism of pancreatic ion …

Purpose of review Premature intracellular activation of pancreatic zymogens leads to the
initiation of pancreatitis, which in up to 25% leads to chronic tissue destruction, exocrine and …

Various organosulfur compounds, such as dimethyl trisulfide (DMTS), display anti-
inflammatory properties. We aimed to examine the effects of DMTS on acute pancreatitis …

A cardinal function of the pancreatic duct is to secrete alkaline fluid containing 140< ts> mM
HCO 3‐. Fluid secretion starts with acinar cells secreting a small volume of isotonic NaCl …

Purpose of review Premature intracellular activation of pancreatic zymogens leads to the
initiation of pancreatitis, which in up to 25% leads to chronic tissue destruction, exocrine and …