[HTML][HTML] Implications of butyrate and its derivatives for gut health and animal production

A Bedford, J Gong - Animal Nutrition, 2018 - Elsevier
Butyrate is produced by microbial fermentation in the large intestine of humans and animals.
It serves as not only a primary nutrient that provides energy to colonocytes, but also a …

The role of butyrate on colonic function

HM Hamer, D Jonkers, K Venema… - Alimentary …, 2008 - Wiley Online Library
Background Butyrate, a short‐chain fatty acid, is a main end‐product of intestinal microbial
fermentation of mainly dietary fibre. Butyrate is an important energy source for intestinal …

[HTML][HTML] Mechanisms linking dietary fiber, gut microbiota and colon cancer prevention

H Zeng, DL Lazarova, M Bordonaro - World journal of …, 2014 - ncbi.nlm.nih.gov
Many epidemiological and experimental studies have suggested that dietary fiber plays an
important role in colon cancer prevention. These findings may relate to the ability of fiber to …

Butyrate and colorectal cancer: the role of butyrate transport

P Gonçalves, F Martel - Current drug metabolism, 2013 - ingentaconnect.com
Colorectal cancer (CRC) is one of the most common solid tumors worldwide. A diet rich in
dietary fiber is associated with a reduction in its risk. Butyrate (BT) is one of the main end …

Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts

C Lozupone, K Faust, J Raes, JJ Faith… - Genome …, 2012 - genome.cshlp.org
We lack a deep understanding of genetic and metabolic attributes specializing in microbial
consortia for initial and subsequent waves of colonization of our body habitats. Here we …

Intestinal health functions of colonic microbial metabolites: a review

R Havenaar - Beneficial microbes, 2011 - wageningenacademic.com
This review tries to find a scientific answer on the following two questions:(1) to what extent
do we understand the specific role of colonic microbial metabolites, especially short-chain …

Targeting the hindgut to improve health and performance in cattle

MV Sanz-Fernandez, JB Daniel, DJ Seymour… - Animals, 2020 - mdpi.com
Simple Summary It is well established that the functions of the gastrointestinal tract go
beyond the digestion and absorption of nutrients. For instance, its constant contact with the …

Lactobacillus plantarum-derived metabolites sensitize the tumor-suppressive effects of butyrate by regulating the functional expression of SMCT1 in 5-FU-resistant …

HJ Kim, JJ An, EM Ha - Journal of Microbiology, 2022 - Springer
A critical obstacle to the successful treatment of colorectal cancer (CRC) is chemoresistance.
Chemoresistant CRC cells contribute to treatment failure by providing a mechanism of drug …

A double‐edged sword: Role of butyrate in the oral cavity and the gut

X Guan, W Li, H Meng - Molecular Oral Microbiology, 2021 - Wiley Online Library
Butyrate, a four‐carbon short‐chain fatty acid (SCFA), is a metabolite of anaerobic bacteria.
Butyrate has primarily been described as an energy substance in the studies on the …

Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk?

M Bordonaro, DL Lazarova, AC Sartorelli - Cell Cycle, 2008 - Taylor & Francis
Studies on the protective role of dietary fiber and its breakdown product butyrate against
colorectal cancer (CRC) have yielded inconsistent findings. We have reported that butyrate …