Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …

Virus-like particles (VLPs) have significant potential as artificial vaccines and drug delivery
systems. The ability to control their size has wide ranging utility but achieving such …

Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A
major challenge lies in distinguishing between the roles of the interaction between coat …

Viral outbreaks remain a serious threat to human and animal populations and motivate the
continued development of antiviral drugs and vaccines, which in turn benefits from a …

Sculpting a flat patch of membrane into an endocytic vesicle requires curvature generation
on the cell surface, which is the primary function of the endocytosis machinery. Using super …

Hepatitis B virus (HBV) is an endemic, chronic virus that leads to 800000 deaths per year.
Central to the HBV lifecycle, the viral core has a protein capsid assembled from many copies …

Simple RNA viruses self-assemble spontaneously and encapsulate their genome into a
shell called the capsid. This process is mainly driven by the attractive electrostatics …