Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Atherosclerosis and inflammation: insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
Extracellular vesicles engineering by silicates-activated endothelial progenitor cells for myocardial infarction treatment in male mice
B Yu, H Li, Z Zhang, P Chen, L Wang, X Fan… - Nature …, 2023 - nature.com
Extracellular vesicles have shown good potential in disease treatments including ischemic
injury such as myocardial infarction. However, the efficient production of highly active …
injury such as myocardial infarction. However, the efficient production of highly active …
Inflammatory chemokines in atherosclerosis
Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …
formation of occlusive or rupture-prone lesions in large arteries. Complications of …
[HTML][HTML] Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts
Y Zhuang, C Zhang, M Cheng, J Huang, Q Liu… - Bioactive Materials, 2021 - Elsevier
Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,
which even result in dysfunction and death. Vascular regeneration or artificial vascular graft …
which even result in dysfunction and death. Vascular regeneration or artificial vascular graft …
Pathophysiology and immune dysfunction in endometriosis
SH Ahn, SP Monsanto, C Miller… - BioMed research …, 2015 - Wiley Online Library
Endometriosis is an estrogen‐dependent, chronic, proinflammatory disease prevalent in
10% of women of reproductive age worldwide. Characterized by the growth of endometrium …
10% of women of reproductive age worldwide. Characterized by the growth of endometrium …
Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions
SK Sanganalmath, R Bolli - Circulation research, 2013 - Am Heart Assoc
Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …
remains poor, and current therapeutic approaches are palliative in the sense that they do not …
Response of the cerebral vasculature following traumatic brain injury
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing
G Chamberlain, J Fox, B Ashton, J Middleton - Stem cells, 2007 - academic.oup.com
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
DJ Ceradini, AR Kulkarni, MJ Callaghan, OM Tepper… - Nature medicine, 2004 - nature.com
The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly
understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates …
understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates …