Characterizing regional drug delivery within the nasal airways
Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …
the site of deposition constitutes the first point of contact of the body with the drug …
CFD-PK model for nasal suspension sprays: Validation with human adult in vivo data for triamcinolone acetonide
The objectives of this study were to expand and implement a Computational Fluid Dynamics
(CFD)-Dissolution, Absorption and Clearance (DAC)-Pharmacokinetics (PK) multi-physics …
(CFD)-Dissolution, Absorption and Clearance (DAC)-Pharmacokinetics (PK) multi-physics …
Prediction of Transport and Deposition of Porous Particles in the Respiratory System Using Eulerian–Lagrangian Approach
S Eshaghi, H Khaleghi… - International Journal for …, 2024 - Wiley Online Library
Deep lung delivery is crucial for respiratory disease treatment. Although nano and
submicron particles exhibited a good deposition efficiency in deep regions of the lung …
submicron particles exhibited a good deposition efficiency in deep regions of the lung …
MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function
J Lin, J Unge, T Gonen - bioRxiv, 2024 - biorxiv.org
The detailed understanding of fluticasone, a widely prescribed medicine for allergic rhinitis,
asthma, and chronic obstructive pulmonary disease (COPD), has not been complete due to …
asthma, and chronic obstructive pulmonary disease (COPD), has not been complete due to …