Infectious diseases are emerging globally at an unprecedented rate while global food
demand is projected to increase sharply by 2100. Here, we synthesize the pathways by …

Executive summary Far-reaching changes to the structure and function of the Earth's natural
systems represent a growing threat to human health. And yet, global health has mainly …

Land use change—for example, the conversion of natural habitats to agricultural or urban
ecosystems—is widely recognized to influence the risk and emergence of zoonotic disease …

Disease outbreaks and pandemics have long played a role in societal and economic
change. However, the nature of such change is selective, meaning that it is sometimes …

It is relatively well accepted that climate change can affect human pathogenic diseases;
however, the full extent of this risk remains poorly quantified. Here we carried out a …

Social cohesion involves the interpersonal dynamics and sense of connection among
people. Increased social cohesion can be associated with various physical and …

As the world warms due to rising greenhouse gas concentrations, the Earth system moves
toward climate states without societal precedent, challenging adaptation. Past Earth system …

Nanosafety is paramount considering the risks associated with manufactured nanomaterials
(MNMs) whose implications could outweigh their advantages for environmental applications …

We live amid a global wave of anthropogenically driven biodiversity loss: species and
population extirpations and, critically, declines in local species abundance. Particularly …

The central challenge of the 21st century is to develop economic, social, and governance
systems capable of ending poverty and achieving sustainable levels of population and …