To date, 33 human platelet alloantigens (HPA s) have been identified on six functionally
important platelet glycoprotein (GP) complexes and have been implicated in alloimmune …

Neonatal alloimmune thrombocytopenia,(NAIT) is caused by maternal antibodies raised
against alloantigens carried on fetal platelets. Although many cases are mild, NAIT is a …

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass
spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were …

BACKGROUND: Neonatal alloimmune thrombocytopenia (NATP) caused by fetomaternal
mismatch for human platelet (PLT) alloantigens (HPAs) complicates approximately 1 in 1000 …

In the context of additional characterization of the pathoetiologic associations of heritable
hypofibrinolysis and thrombophilia with osteonecrosis of the hip, the authors assessed 15 …

Polymorphic structures of the neutrophil Fcγreceptor IIIb (FcγRIIIb) result in alloantibody
formation that causes alloimmune neonatal neutropenia and transfusion reactions …

T HE ARREST of hemorrhage associated with an increase in the patient s platelet count
after blood transfusion was first reported by Duke in 1910.1 It was not until the 1960s that …

Now in its Third Edition, this authoritative text continues to provide a comprehensive and
systematic review of the biology, pathobiology, and clinical disorders of the hemostatic …

BACKGROUND: The study of the immunogenetics of the human platelet antigens is
important to the improvement of diagnosis and genetic counseling and to the development …

Typing for human platelet antigens (HPA) is useful in a variety of clinical situations. We
developed a method for genotyping for HPA-1,-2,-3 and-5 by means of the PCR …