Technological advances now enable routine measurement of mRNA and protein
abundances, and estimates of their rates of synthesis and degradation that inform on their …

Mass spectrometry based proteomics and other technologies have matured to enable
routine quantitative, system-wide analysis of concentrations, modifications, and interactions …

Stem cell differentiation is a highly dynamic process involving pervasive changes in gene
expression. The large majority of existing studies has characterized differentiation at the …

Background The oocyte-to-embryo transition (OET) converts terminally differentiated
gametes into a totipotent embryo and is critically controlled by maternal mRNAs and …

Natural direct current electric fields (DC EFs) within tissues undergoing angiogenesis have
the potential to influence vessel formation, but how they affect endothelial cells is not clear …

Recent advances in proteomics allow the accurate measurement of abundances for
thousands of proteins and phosphoproteins from multiple samples in parallel. Therefore, for …

Extracellular matrices (ECMs) are essential for the architecture and function of animal
tissues. ECMs have been thought to be highly stable structures; however, too much stability …

Simple Summary Chronic lymphocytic leukaemia (CLL) is the most frequent type of
leukaemia with a highly variable presentation, clinical course, and outcome. The overall aim …

Proteomics approaches designed to catalogue all open reading frames (ORFs) under a
defined set of growth conditions of an organism have flourished in recent years. However …

Protein synthesis and degradation are essential processes that regulate cell status. Because
labeling in bulky organs, such as fruits, is difficult, we developed a modeling approach to …