Next-generation analysis of gene expression regulation–comparing the roles of synthesis and degradation
Technological advances now enable routine measurement of mRNA and protein
abundances, and estimates of their rates of synthesis and degradation that inform on their …
abundances, and estimates of their rates of synthesis and degradation that inform on their …
Exploiting interdata relationships in next-generation proteomics analysis
B Vitrinel, HWL Koh, FM Kar, S Maity… - Molecular & Cellular …, 2019 - ASBMB
Mass spectrometry based proteomics and other technologies have matured to enable
routine quantitative, system-wide analysis of concentrations, modifications, and interactions …
routine quantitative, system-wide analysis of concentrations, modifications, and interactions …
Integration of a multi-omics stem cell differentiation dataset using a dynamical model
PR van den Berg, NMLP Bérenger-Currias… - PLoS …, 2023 - journals.plos.org
Stem cell differentiation is a highly dynamic process involving pervasive changes in gene
expression. The large majority of existing studies has characterized differentiation at the …
expression. The large majority of existing studies has characterized differentiation at the …
Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition
H Zhang, S Ji, K Zhang, Y Chen, J Ming, F Kong… - Genome Biology, 2023 - Springer
Background The oocyte-to-embryo transition (OET) converts terminally differentiated
gametes into a totipotent embryo and is critically controlled by maternal mRNAs and …
gametes into a totipotent embryo and is critically controlled by maternal mRNAs and …
Electrical stimulation directs migration, enhances and orients cell division and upregulates the chemokine receptors CXCR4 and CXCR2 in endothelial cells
F Cunha, AM Rajnicek, CD McCaig - Journal of Vascular Research, 2019 - karger.com
Natural direct current electric fields (DC EFs) within tissues undergoing angiogenesis have
the potential to influence vessel formation, but how they affect endothelial cells is not clear …
the potential to influence vessel formation, but how they affect endothelial cells is not clear …
Proteomics and phosphoproteomics in precision medicine: applications and challenges
G Giudice, E Petsalaki - Briefings in bioinformatics, 2019 - academic.oup.com
Recent advances in proteomics allow the accurate measurement of abundances for
thousands of proteins and phosphoproteins from multiple samples in parallel. Therefore, for …
thousands of proteins and phosphoproteins from multiple samples in parallel. Therefore, for …
Dynamic movement and turnover of extracellular matrices during tissue development and maintenance
Y Matsubayashi - Fly, 2022 - Taylor & Francis
Extracellular matrices (ECMs) are essential for the architecture and function of animal
tissues. ECMs have been thought to be highly stable structures; however, too much stability …
tissues. ECMs have been thought to be highly stable structures; however, too much stability …
Low BACH2 expression predicts adverse outcome in chronic lymphocytic leukaemia
Simple Summary Chronic lymphocytic leukaemia (CLL) is the most frequent type of
leukaemia with a highly variable presentation, clinical course, and outcome. The overall aim …
leukaemia with a highly variable presentation, clinical course, and outcome. The overall aim …
Mass-Spectrometry-Based Near-Complete Draft of the Saccharomyces cerevisiae Proteome
Proteomics approaches designed to catalogue all open reading frames (ORFs) under a
defined set of growth conditions of an organism have flourished in recent years. However …
defined set of growth conditions of an organism have flourished in recent years. However …
Modeling protein destiny in developing fruit
I Belouah, C Nazaret, P Pétriacq, S Prigent… - Plant …, 2019 - academic.oup.com
Protein synthesis and degradation are essential processes that regulate cell status. Because
labeling in bulky organs, such as fruits, is difficult, we developed a modeling approach to …
labeling in bulky organs, such as fruits, is difficult, we developed a modeling approach to …