New developments in anti-malarial target candidate and product profiles

JN Burrows, S Duparc, WE Gutteridge… - Malaria journal, 2017 - Springer
A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis

T Laelago, T Yohannes, G Tsige - Italian journal of pediatrics, 2020 - Springer
Background Preterm birth (PTB) can be caused by different factors. The factors can be
classified into different categories: socio demographic, obstetric, reproductive health …

[PDF][PDF] WHO guidelines for malaria, 3 June 2022

World Health Organization - 2022 - apps.who.int
This document is a PDF generated from the WHO Guidelines for malaria hosted on the
MAGICapp online platform: https://app. magicapp. org/#/guideline/6287. Each time the …

First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of observational studies

S Dellicour, E Sevene, R McGready, H Tinto… - PLoS …, 2017 - journals.plos.org
Background Animal embryotoxicity data, and the scarcity of safety data in human
pregnancies, have prevented artemisinin derivatives from being recommended for malaria …

Malaria: an update on current chemotherapy

BJ Visser, M van Vugt, MP Grobusch - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study

KA Moore, JA Simpson, MK Paw… - The Lancet Infectious …, 2016 - thelancet.com
Background Artemisinins, the most effective antimalarials available, are not recommended
for falciparum malaria during the first trimester of pregnancy because of safety concerns …

Treatment of uncomplicated and severe malaria during pregnancy

U D'Alessandro, J Hill, J Tarning, C Pell… - The Lancet infectious …, 2018 - thelancet.com
Over the past 10 years, the available evidence on the treatment of malaria during pregnancy
has increased substantially. Owing to their relative ease of use, good sensitivity and …

Treating severe malaria in pregnancy: a review of the evidence

SD Kovacs, MJ Rijken, A Stergachis - Drug Safety, 2015 - Springer
Severe malaria in pregnancy is a large contributor to maternal morbidity and mortality.
Intravenous quinine has traditionally been the treatment drug of choice for severe malaria in …

Clinical management of Plasmodium knowlesi malaria

BE Barber, MJ Grigg, DJ Cooper… - Advances in …, 2021 - Elsevier
The zoonotic parasite Plasmodium knowlesi has emerged as an important cause of human
malaria in parts of Southeast Asia. The parasite is indistinguishable by microscopy from the …

Antimalarial drugs for treating and preventing malaria in pregnant and lactating women

M Saito, ME Gilder, R McGready… - Expert Opinion on Drug …, 2018 - Taylor & Francis
Introduction: Malaria in pregnancy and postpartum cause maternal mortality and adverse
fetal outcomes. Efficacious and safe antimalarials are needed to treat and prevent such …