Iron, as an essential trace element for the organism, is vital for maintaining the organism's
health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus …

Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

We have previously demonstrated that placental 11β-hydroxysteroid dehydrogenase type 2
(11β-HSD2) dysfunction contributes to PE pathogenesis. We sought to elucidate molecular …

Maternal metabolism during pregnancy shapes offspring health via in utero programming. In
the Healthy Start study, we identified five subgroups of pregnant women based on …

Mitochondrial fatty acid oxidation (FAO) is lower in placentas with pre-eclampsia. The aim of
our study was to compare the placental mRNA expression of FAO enzymes in healthy …

Introduction Our understanding of the etiology of preterm birth (PTB) is incomplete; however,
recent evidence has found a strong association between placental dysfunction and PTB …

Preeclampsia is a multisystem pregnancy disorder that is characterized by different degrees
of placental malperfusion, with release of antiangiogenic factors into the circulation, leading …

Background Gestational hypertension (GH) is a severe complication that occurs after 20
weeks of pregnancy; however, its molecular mechanisms are not yet fully understood …

Preeclampsia is a life‐threatening pregnancy disorder. Current clinical assays cannot
predict the onset of preeclampsia until the late 2nd trimester, which often leads to poor …

Dementia with Lewy Bodies (DLB) is a complex neurodegenerative disorder that often
overlaps clinically with Alzheimer's disease (AD), presenting challenges in accurate …