Intravital imaging to study cancer progression and metastasis

D Entenberg, MH Oktay, JS Condeelis - Nature Reviews Cancer, 2023 - nature.com
Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

Second Near‐Infrared (NIR‐II) Window for Imaging‐Navigated Modulation of Brain Structure and Function

K Zhang, FR Chen, L Wang, J Hu - Small, 2023 - Wiley Online Library
For a long time, optical imaging of the deep brain with high resolution has been a challenge.
Recently, with the advance in second near‐infrared (NIR‐II) bioimaging techniques and …

Metastasis from the tumor interior and necrotic core formation are regulated by breast cancer-derived angiopoietin-like 7

A Yamamoto, Y Huang, BA Krajina… - Proceedings of the …, 2023 - National Acad Sciences
Necrosis in the tumor interior is a common feature of aggressive cancers that is associated
with poor clinical prognosis and the development of metastasis. How the necrotic core …

Dynamic Multiplex tissue imaging in inflammation research

S Uderhardt, G Neag… - Annual Review of …, 2024 - annualreviews.org
Inflammation is a highly dynamic process with immune cells that continuously interact with
each other and parenchymal components as they migrate through tissue. The dynamic …

Microlenses fabricated by two‐photon laser polymerization for cell imaging with non‐linear excitation microscopy

M Marini, A Nardini, R Martínez Vázquez… - Advanced Functional …, 2023 - Wiley Online Library
Non‐linear excitation microscopy offers several advantages for in‐vivo imaging compared to
conventional confocal techniques. However, tissue penetration can still be an issue due to …

Restoration of mitochondria axonal transport by adaptor Disc1 supplementation prevents neurodegeneration and rescues visual function

H Quintero, Y Shiga, N Belforte, L Alarcon-Martinez… - Cell reports, 2022 - cell.com
Deficits in mitochondrial transport are a common feature of neurodegenerative diseases. We
investigated whether loss of components of the mitochondrial transport machinery impinge …

Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome

M Yildirim, C Delepine, D Feldman, VA Pham, S Chou… - Elife, 2022 - elifesciences.org
Human cerebral organoids are unique in their development of progenitor-rich zones akin to
ventricular zones from which neuronal progenitors differentiate and migrate radially …

Multi‐photon microscopy

J Sanderson - Current Protocols, 2023 - Wiley Online Library
In this series of papers on light microscopy imaging, we have covered the fundamentals of
microscopy, super‐resolution microscopy, and lightsheet microscopy. This last review …

Infiltrating CD8+ T cells and M2 macrophages are retained in tumor matrix tracks enriched in low tension fibronectin fibers

CM Fonta, T Loustau, C Li, SP Surendran, U Hansen… - Matrix Biology, 2023 - Elsevier
Tracks rich in matrix and cells, as described in several cancer types, have
immunosuppressive functions and separate tumor nests and stroma, yet their origin is …

Microfluidic vascular models of tumor cell extravasation

S Kim, Z Wan, JS Jeon, RD Kamm - Frontiers in Oncology, 2022 - frontiersin.org
Emerging microfluidic disease models have amply demonstrated their value in many fields
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …