Neuropathic pain is a common and debilitating modality of chronic pain induced by a lesion
or disease of the somatosensory nervous system. Albeit the elucidation of numerous …

It is generally believed that immune activation can elicit pain through production of
inflammatory mediators that can activate nociceptive sensory neurons. Emerging evidence …

Pain is a common symptom of many diseases with a high incidence rate. Clinically, drug
treatment, as the main method to relieve pain at present, is often accompanied by different …

The nervous and immune systems are the primary sensory interfaces of the body, allowing it
to recognize, process, and respond to various stimuli from both the external and internal …

Aims Paclitaxel (PTX) is extensively utilized in the management of diverse solid tumors,
frequently resulting in paclitaxel‐induced peripheral neuropathy (PIPN). The present study …

The advent of targeted molecular therapy and immunotherapy in clinical oncology heralded
explosive growth of data from the clinic that would shed new light on basic biology and …

A dor é compreendida como uma resposta gerada após o reconhecimento de um estímulo
nocivo, podendo estar associada à uma lesão real ou potencial. Porém, processos …

Background: Treatment strategies for refractory recurrent or metastatic cervical cancer (R/M
CC) are scarce. The synergistic antitumor effects of toripalimab plus standard therapy as first …