The issue of heterogeneity of MSC-based advanced therapy medicinal products–a review
AB Česnik, U Švajger - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Mesenchymal stromal stem cells (MSCs) possess a remarkable potential for numerous
clinical applications due to their unique properties including self-renewal …
clinical applications due to their unique properties including self-renewal …
Single-cell RNA-seq highlights heterogeneity in human primary Wharton's jelly mesenchymal stem/stromal cells cultured in vitro
C Sun, L Wang, H Wang, T Huang, W Yao, J Li… - Stem Cell Research & …, 2020 - Springer
Background Mesenchymal stem/stromal cells (MSCs) are multipotent cells with a promising
application potential in regenerative medicine and immunomodulation. However, MSCs …
application potential in regenerative medicine and immunomodulation. However, MSCs …
Proteomic and transcriptomic approaches for studying bone regeneration in health and systemically compromised conditions
E Calciolari, N Donos - PROTEOMICS–Clinical Applications, 2020 - Wiley Online Library
Bone regeneration is a complex biological process, where the molecular mechanisms are
only partially understood. In an ageing population, where the prevalence of chronic …
only partially understood. In an ageing population, where the prevalence of chronic …
Mesenchymal Stem/Stromal cells and fibroblasts: their roles in tissue Injury and Regeneration, and age-related degeneration
J Zupan - … —Advances in Inflammation, Autoimmunity and Cancer, 2021 - books.google.com
Mesenchymal stem/stromal cells (MSCs) and fibroblasts are present in normal tissues to
support tissue homeostasis. Both share common pathways and have a number of common …
support tissue homeostasis. Both share common pathways and have a number of common …
First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse …
F Siddiqui, D Gallagher, H Shuster-Hyman… - Journal of …, 2023 - Springer
Abstract Background The Kynurenine Pathway (KP) of tryptophan degradation and
glutamate toxicity is implicated in several neurological disorders, including depression. The …
glutamate toxicity is implicated in several neurological disorders, including depression. The …
Bone Marrow Derived Mesenchymal Stromal Cells Promote Vascularization and Ciliation in Airway Mucosa Tri-Culture Models in Vitro
AE Luengen, M Cheremkhina… - … in bioengineering and …, 2022 - frontiersin.org
Patients suffering from irresectable tracheal stenosis often face limited treatment options
associated with low quality of life. To date, an optimal tracheal replacement strategy does …
associated with low quality of life. To date, an optimal tracheal replacement strategy does …
Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors
W Chen, C Wang, ZX Yang, F Zhang, W Wen… - Communications …, 2023 - nature.com
Mesenchymal stromal cells (MSCs) have great value in cell therapies. The MSC therapies
have many challenges due to its inconsistent potency and limited quantity. Here, we report a …
have many challenges due to its inconsistent potency and limited quantity. Here, we report a …
Transcriptome analysis reveals high similarities between adult human cardiac stem cells and neural crest-derived stem cells
AL Höving, K Sielemann, JFW Greiner, B Kaltschmidt… - Biology, 2020 - mdpi.com
Simple Summary The regeneration of nearly all organs of the human body mainly depends
on the functionality of adult stem cell populations that reside in their respective niches and …
on the functionality of adult stem cell populations that reside in their respective niches and …
[PDF][PDF] First Trimester Human Umbilical Cord Perivascular cells (HUCPVC) Modulate the Kynurenine Pathway and Glutamate Neurotransmission in an LPS-induced …
F Siddiqui, D Gallagher, H Shuster-Hyman, L Lopez… - 2022 - scholar.archive.org
Background The Kynurenine Pathway (KP) of tryptophan degradation and glutamate toxicity
is implicated in several neurological disorders, including depression. Although …
is implicated in several neurological disorders, including depression. Although …
[PDF][PDF] Bone Marrow Derived Mesenchymal Stromal Cells Promote Vascularization and Ciliation in Airway Mucosa Tri-Culture Models in Vitro. Front. Bioeng …
AE Luengen, M Cheremkhina… - Frontiers in …, 2022 - publications.rwth-aachen.de
ORIGINAL RESEARCH published: 17 June 2022 doi: 10.3389/fbioe. 2022.872275 more
branched and extended. Concentrations of pro-angiogenic and inflammatory cytokines, in …
branched and extended. Concentrations of pro-angiogenic and inflammatory cytokines, in …