Brain and peripheral atypical inflammatory mediators potentiate neuroinflammation and neurodegeneration
D Kempuraj, R Thangavel, GP Selvakumar… - Frontiers in cellular …, 2017 - frontiersin.org
Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving …
excessive and chronic inflammatory responses can lead to deleterious effects involving …
Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases
S Gangemi, E Gofita, C Costa… - International …, 2016 - spandidos-publications.com
Pesticides can exert numerous effects on human health as a consequence of both
environmental and occupational exposures. The available knowledge base suggests that …
environmental and occupational exposures. The available knowledge base suggests that …
Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. It is
characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of …
characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of …
Anti-inflammatory activity of ursolic acid in MPTP-induced parkinsonian mouse model
SN Rai, W Zahra, SS Singh, H Birla, C Keswani… - Neurotoxicity …, 2019 - Springer
Neuroinflammation plays an important role in the progression of Parkinson's disease (PD)
and hence may represent a target for treatment. The drugs used currently for PD only …
and hence may represent a target for treatment. The drugs used currently for PD only …
Immunomodulatory effects of dopamine in inflammatory diseases
Y Feng, Y Lu - Frontiers in immunology, 2021 - frontiersin.org
Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …
β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson …
Parkinson disease (PD) is a neurodegenerative disease characterized by progressive
dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The …
dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The …
New insights into the ameliorative effects of ferulic acid in pathophysiological conditions
S Ghosh, P Basak, S Dutta, S Chowdhury… - Food and Chemical …, 2017 - Elsevier
Ferulic acid, a natural phytochemical has gained importance as a potential therapeutic
agent by virtue of its easy commercial availability, low cost and minimal side-effects. It is a …
agent by virtue of its easy commercial availability, low cost and minimal side-effects. It is a …
Neuroprotective potential of ferulic acid in the rotenone model of Parkinson's disease
S Ojha, H Javed, S Azimullah… - Drug design …, 2015 - Taylor & Francis
Parkinson's disease (PD) is a chronic, progressive, and the second most common form of
neurodegenerative disorders. In order to explore novel agents for the treatment of PD, in the …
neurodegenerative disorders. In order to explore novel agents for the treatment of PD, in the …
Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?
Exposure to environmental toxins is associated with a variety of age‐related diseases
including cancer and neurodegeneration. For example, in Parkinson's disease (PD), chronic …
including cancer and neurodegeneration. For example, in Parkinson's disease (PD), chronic …
Inflammation in Parkinson's disease
Parkinson's disease (PD) is a common neurodegenerative disease that is characterized by
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …