MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are
some of the most important biopharmaceuticals that are in commercial space as future …

MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …

Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …

MicroRNAs (miRNAs) constitute a class of small cellular RNAs (typically 21–23nt) that
function as post-transcriptional regulators of gene expression. Current estimates indicate …

Despite their clear importance as a class of regulatory molecules, pinpointing the relevance
of individual miRNAs has been challenging. Studies querying miRNA functions by …

First recognized as regulators of development in worms and fruitflies, microRNAs are
emerging as pivotal modulators of mammalian cardiovascular development and disease …

Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

The microRNA (miRNA)“sponge” method was introduced three years ago as a means to
create continuous miRNA loss of function in cell lines and transgenic organisms. Sponge …