Klotho has been recognized as a gene involved in the aging process in mammals for over
30 years, where it regulates phosphate homeostasis and the activity of members of the …

Although high-protein diets continue to be popular for weight loss and type 2 diabetes,
evidence suggests that worsening renal function may occur in individuals with—and …

Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

The patient with chronic kidney disease (CKD) represents an extreme model for
arteriosclerosis, vascular calcification, and bone disorders, all of which are also associated …

Nanotechnology is a rapidly developing technology that will have a significant impact on
product development in the next few years. The technology is already being employed in …

It is becoming more feasible to use nano-enabled agricultural products such as
nanofertilizers and nanopesticides to improve the efficiency of agrochemical delivery to crop …

Disturbances in phosphate homeostasis are common in patients with chronic kidney
disease. As kidney function declines, circulating concentrations of phosphate and the …

The consumption of ultra-processed food (UPF) keeps rising, and at the same time, an
increasing number of epidemiological studies are linking high rates of consumption of UPF …

Hyperphosphatemia has consistently been shown to be associated with dismal outcome in a
wide variety of populations, particularly in chronic kidney disease (CKD). Compelling …

Although phosphorus is an essential nutrient required for multiple physiological functions,
recent research raises concerns that high phosphorus intake could have detrimental effects …