Immunosenescence and human vaccine immune responses
SN Crooke, IG Ovsyannikova, GA Poland… - Immunity & …, 2019 - Springer
The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …
“immunosenescence”—has been generally associated with an increased susceptibility to …
Biology of infection and disease pathogenesis to guide RSV vaccine development
S Boyoglu-Barnum, T Chirkova… - Frontiers in …, 2019 - frontiersin.org
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract disease
in young children and a substantial contributor to respiratory tract disease throughout life …
in young children and a substantial contributor to respiratory tract disease throughout life …
Longitudinal humoral analysis in RSV-infected infants identifies pre-existing RSV strain-specific G and evolving cross-reactive F antibodies
Respiratory syncytial virus (RSV) is among the most common causes of lower respiratory
tract infection (LRTI) and hospitalization in infants. However, the mechanisms of immune …
tract infection (LRTI) and hospitalization in infants. However, the mechanisms of immune …
Host responses to respiratory syncytial virus infection
A Agac, SM Kolbe, M Ludlow, ADME Osterhaus… - Viruses, 2023 - mdpi.com
Respiratory syncytial virus (RSV) infections are a constant public health problem, especially
in infants and older adults. Virtually all children will have been infected with RSV by the age …
in infants and older adults. Virtually all children will have been infected with RSV by the age …
Broad antibody and cellular immune response from a phase 2 clinical trial with a novel multivalent poxvirus-based respiratory syncytial virus vaccine
E Jordan, SJ Lawrence, TPH Meyer… - The Journal of …, 2021 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a major cause of severe respiratory disease
in young children and the elderly. Protective immunity is not generated after repeated …
in young children and the elderly. Protective immunity is not generated after repeated …
Considerations for a respiratory syncytial virus vaccine targeting an elderly population
LM Stephens, SM Varga - Vaccines, 2021 - mdpi.com
Respiratory syncytial virus (RSV) is most commonly associated with acute lower respiratory
tract infections in infants and children. However, RSV also causes a high disease burden in …
tract infections in infants and children. However, RSV also causes a high disease burden in …
Immunity cell responses to RSV and the role of antiviral inhibitors: a systematic review
G Churiso, G Husen, D Bulbula… - Infection and drug …, 2022 - Taylor & Francis
Antigen-presenting cells recognize respiratory syncytial virus antigens, and produce
cytokines and chemokines that act on immune cells. Dendritic cells play the main role in …
cytokines and chemokines that act on immune cells. Dendritic cells play the main role in …
Immunopathogenesis of Nipah virus infection and associated immune responses
Pandemics in the last two centuries have been initiated by causal pathogens that include
Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (eg, the H1N1 pandemic of 2009) …
Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (eg, the H1N1 pandemic of 2009) …
Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations
NC Salisch, A Izquierdo Gil, DN Czapska-Casey… - npj Vaccines, 2019 - nature.com
Abstract Respiratory Syncytial Virus (RSV) can cause severe respiratory disease, yet a
licensed vaccine is not available. We determined the immunogenicity of two homologous …
licensed vaccine is not available. We determined the immunogenicity of two homologous …
[HTML][HTML] Environmental cadmium enhances lung injury by respiratory syncytial virus infection
Cadmium (Cd) is a naturally occurring environmental toxicant that disrupts mitochondrial
function at occupational exposure levels. The impacts of Cd exposure at low levels through …
function at occupational exposure levels. The impacts of Cd exposure at low levels through …