Imperatorin: a review of its pharmacology, toxicity and pharmacokinetics

M Deng, L Xie, L Zhong, Y Liao, L Liu, X Li - European Journal of …, 2020 - Elsevier
As a naturally occurring furanocoumarin, the medicinal value of imperatorin has been
studied more and more. We hope to provide useful information for the further development of …

[HTML][HTML] Imperatorin–pharmacological meaning and analytical clues: profound investigation

E Kozioł, K Skalicka-Woźniak - Phytochemistry Reviews, 2016 - Springer
Imperatorin, a furanocoumarin derivative, has many documented pharmacological
properties which make it a candidate for possible drug development. In this review, the …

Identification of metabolites of deoxyschizandrin in rats by UPLC–Q-TOF-MS/MS based on multiple mass defect filter data acquisition and multiple data processing …

M Liu, S Zhao, Z Wang, Y Wang, T Liu, S Li… - … of Chromatography B, 2014 - Elsevier
Deoxyschizandrin is an active lignin ingredient originating from Schisandra chinensis
(Turcz.) Baill or Schisandrae Sphenantherae Fructus. In the present study, a novel and …

An enhanced strategy integrating offline superimposed two-dimensional separation with mass defect filter and diagnostic ion filter: Comprehensive characterization of …

Y An, W Wei, H Li, Z Li, C Yao, H Qu, S Yao… - … of Chromatography A, 2021 - Elsevier
The inherent complexity of traditional Chinese medicines necessitates the application of
multi-dimensional information to accomplish comprehensive profiling and confirmative …

An integrated strategy for the systematic characterization and discovery of new indole alkaloids from Uncaria rhynchophylla by UHPLC/DAD/LTQ-Orbitrap-MS

H Pan, W Yang, Y Zhang, M Yang, R Feng… - Analytical and …, 2015 - Springer
The exploration of new chemical entities from herbal medicines may provide candidates for
the in silico screening of drug leads. However, this significant work is hindered by the …

Identification of metabolites of oridonin in rats with a single run on UPLC-Triple-TOF-MS/MS system based on multiple mass defect filter data acquisition and multiple …

T Tian, Y Jin, Y Ma, W Xie, H Xu, K Zhang… - … of Chromatography B, 2015 - Elsevier
Oridonin (ORI) is an active natural ent-kaurane diterpenoid ingredient originating from well-
known traditional Chinese herb medicine and is expected to be pursued as a new …

UHPLC-Q-TOF-MS/MS Method Based on Four-Step Strategy for Metabolism Study of Fisetin in Vitro and in Vivo

X Zhang, J Yin, C Liang, Y Sun… - Journal of agricultural and …, 2017 - ACS Publications
Fisetin has been identified as an anticancer agent with antiangiogenic properties in mice.
However, its metabolism in vitro (rat liver microsomes) and in vivo (rats) is presently not …

UPLC-QTOF-MS/MS screening and identification of bioactive compounds in fresh, aged, and browned Magnolia denudata flower extracts

YH Joo, MH Nam, N Chung, YK Lee - Food research international, 2020 - Elsevier
The Magnolia denudata flower is used to prepare tea and is often fermented to improve its
flavor. Herein, fresh, aged, and browned M. denudata flower extracts were characterized …

Rapid characterization and identification of the chemical constituents and the metabolites of Du-zhi pill using UHPLC coupled with quadrupole time-of-flight mass …

H Lai, Y Ouyang, G Tian, J Zhao, J Zhang… - … of Chromatography B, 2022 - Elsevier
A reliable method using ultra-performance liquid chromatography coupled with quadrupole
time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was established to conduct a …

Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF …

SH López, MM Ulaszewska, MD Hernando… - … Science and Pollution …, 2014 - Springer
This study describes a comprehensive strategy for detecting and elucidating the chemical
structures of expected and unexpected transformation products (TPs) from chemicals found …