Viral interactions with the cytoskeleton: a hitchhiker's guide to the cell
K Radtke, K Döhner, B Sodeik - Cellular microbiology, 2006 - Wiley Online Library
The actin and microtubule cytoskeleton play important roles in the life cycle of every virus.
During attachment, internalization, endocytosis, nuclear targeting, transcription, replication …
During attachment, internalization, endocytosis, nuclear targeting, transcription, replication …
[HTML][HTML] Life of psi: how full-length HIV-1 RNAs become packaged genomes in the viral particles
M Kuzembayeva, K Dilley, L Sardo, WS Hu - Virology, 2014 - Elsevier
As a member of the retrovirus family, HIV-1 packages its RNA genome into particles and
replicates through a DNA intermediate that integrates into the host cellular genome. The …
replicates through a DNA intermediate that integrates into the host cellular genome. The …
NMR detection of structures in the HIV-1 5′-leader RNA that regulate genome packaging
The 5′-leader of the HIV-1 genome regulates multiple functions during viral replication via
mechanisms that have yet to be established. We developed a nuclear magnetic resonance …
mechanisms that have yet to be established. We developed a nuclear magnetic resonance …
Inhibition of IRF5 hyperactivation protects from lupus onset and severity
The transcription factor IFN regulatory factor 5 (IRF5) is a central mediator of innate and
adaptive immunity. Genetic variations within IRF5 are associated with a risk of systemic …
adaptive immunity. Genetic variations within IRF5 are associated with a risk of systemic …
Specific recognition of the HIV-1 genomic RNA by the Gag precursor
EW Abd El-Wahab, RP Smyth, E Mailler… - Nature …, 2014 - nature.com
During assembly of HIV-1 particles in infected cells, the viral Pr55Gag protein (or Gag
precursor) must select the viral genomic RNA (gRNA) from a variety of cellular and viral …
precursor) must select the viral genomic RNA (gRNA) from a variety of cellular and viral …
The life-cycle of the HIV-1 Gag–RNA complex
E Mailler, S Bernacchi, R Marquet, JC Paillart… - Viruses, 2016 - mdpi.com
Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process
requiring the recruitment of viral and cellular components to the plasma membrane for …
requiring the recruitment of viral and cellular components to the plasma membrane for …
Cell biology of HIV-1 infection of macrophages
CA Carter, LS Ehrlich - Annu. Rev. Microbiol., 2008 - annualreviews.org
HIV infection of macrophages is a critically important component of viral pathogenesis and
progression to AIDS. Although the virus follows the same life cycle in macrophages and T …
progression to AIDS. Although the virus follows the same life cycle in macrophages and T …
Aggresomes and pericentriolar sites of virus assembly: cellular defense or viral design?
T Wileman - Annu. Rev. Microbiol., 2007 - annualreviews.org
Virus replication and virus assembly often occur in virus inclusions or virus factories that
form at pericentriolar sites close to the microtubule organizing center or in specialized …
form at pericentriolar sites close to the microtubule organizing center or in specialized …
Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA
LG Abrahamyan, L Chatel-Chaix… - Journal of cell …, 2010 - journals.biologists.com
Human immunodeficiency virus type 1 (HIV-1) Gag selects for and mediates genomic RNA
(vRNA) encapsidation into progeny virus particles. The host protein, Staufen1 interacts …
(vRNA) encapsidation into progeny virus particles. The host protein, Staufen1 interacts …
Identification of an intracellular trafficking and assembly pathway for HIV‐1 gag
M Perlman, MD Resh - Traffic, 2006 - Wiley Online Library
Retroviral Gag proteins are membrane‐bound polyproteins that are necessary and sufficient
for virus‐like particle (VLP) formation. It is not known how Gag traffics through the cell or how …
for virus‐like particle (VLP) formation. It is not known how Gag traffics through the cell or how …