[HTML][HTML] Dissolving microneedles: Applications and growing therapeutic potential

Z Sartawi, C Blackshields, W Faisal - Journal of Controlled Release, 2022 - Elsevier
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic
compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function …

Microneedle system for tissue engineering and regenerative medicine

Y Zhang, Y Xu, H Kong, J Zhang, HF Chan… - …, 2023 - Wiley Online Library
Global increasing demand for high life quality and length facilitates the development of
tissue engineering and regenerative medicine, which apply multidisciplinary theories and …

Wearable hollow microneedle sensing patches for the transdermal electrochemical monitoring of glucose

M Parrilla, U Detamornrat, J Domínguez-Robles… - Talanta, 2022 - Elsevier
Abstract According to the World Health Organization, about 422 million people worldwide
have diabetes, with 1.5 million deaths directly attributed each year. Therefore, there is still a …

Nanomaterials for photothermal and photodynamic cancer therapy

B Nasseri, E Alizadeh, F Bani, S Davaran… - Applied Physics …, 2022 - pubs.aip.org
In recent years, the role of optically sensitive nanomaterials has become powerful moieties
in therapeutic techniques and has become particularly emphasized. Currently, by the …

Colorimetric microneedle patches for multiplexed transdermal detection of metabolites

DD Zhu, PK Duong, RH Cheah, XY Liu… - Biosensors and …, 2022 - Elsevier
Abstract Skin Interstitial Fluid (ISF) is an alternative source for biomarkers. Herein, a highly
swellable microneedle patch (MNP) to rapidly extract ISF painlessly and bloodlessly is …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

Microneedle-based biosensing

LK Vora, AH Sabri, PE McKenna, A Himawan… - Nature Reviews …, 2024 - nature.com
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …

Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …

K Peng, LK Vora, IA Tekko, AD Permana… - Journal of Controlled …, 2021 - Elsevier
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

Minimally invasive electrochemical continuous glucose monitoring sensors: Recent progress and perspective

Y Zou, Z Chu, J Guo, S Liu, X Ma, J Guo - Biosensors and Bioelectronics, 2023 - Elsevier
Diabetes and its complications are seriously threatening the health and well-being of
hundreds of millions of people. Glucose levels are essential indicators of the health …

Improved topical drug delivery: Role of permeation enhancers and advanced approaches

V Hmingthansanga, N Singh, S Banerjee, S Manickam… - Pharmaceutics, 2022 - mdpi.com
The delivery of drugs via transdermal routes is an attractive approach due to ease of
administration, bypassing of the first-pass metabolism, and the large skin surface area …