Challenges of applying multicellular tumor spheroids in preclinical phase
SJ Han, S Kwon, KS Kim - Cancer cell international, 2021 - Springer
Abstract The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is
becoming an essential tool in cancer research as it expresses an intermediate complexity …
becoming an essential tool in cancer research as it expresses an intermediate complexity …
Aptamers chemistry: Chemical modifications and conjugation strategies
Soon after they were first described in 1990, aptamers were largely recognized as a new
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …
Chitosan-based nanomaterials for drug delivery
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer
Exosomes hold great potential for cancer treatment to deliver therapeutics due to its inherent
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems
R Bajracharya, JG Song, BR Patil, SH Lee, HM Noh… - Drug Delivery, 2022 - Taylor & Francis
Conventional chemotherapy lacking target selectivity often leads to severe side effects,
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …
Chitosan-based nanodelivery systems for cancer therapy: Recent advances
Nowadays, cancer is one of the most prominent issues related to human health since it
causes more than one-tenth of death cases throughout the world. On the other hand, routine …
causes more than one-tenth of death cases throughout the world. On the other hand, routine …
Chitosan-modified PLGA nanoparticles for control-released drug delivery
B Lu, X Lv, Y Le - Polymers, 2019 - mdpi.com
Poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) are well recognized as an ideal drug
delivery carrier for their biocompatibility and biodegradability. In order to overcome the …
delivery carrier for their biocompatibility and biodegradability. In order to overcome the …
Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy
Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
[HTML][HTML] Biomedical applications of aptamer-modified chitosan nanomaterials: An updated review
S Fathi-Karkan, S Mirinejad, F Ulucan-Karnak… - International Journal of …, 2023 - Elsevier
Among polysaccharides of environmental and economic interest, chitosan (CS) is receiving
much attention, particularly in the food and biotechnology industries to encapsulate active …
much attention, particularly in the food and biotechnology industries to encapsulate active …
Programmable and multifunctional DNA‐based materials for biomedical applications
DNA encodes the genetic information; recently, it has also become a key player in material
science. Given the specific Watson–Crick base‐pairing interactions between only four types …
science. Given the specific Watson–Crick base‐pairing interactions between only four types …