Energy is a major driving force for the economic development. Due to the scarcity of fossil
fuels and negative impact on the environment, it is important to develop renewable and …

Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …

Obesity is associated with increased cancer incidence and progression. However, the
relationship between adiposity and cancer remains poorly understood at the mechanistic …

Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as
phytic acid or IP6, with their biological activities received much attention for their role in …

Discovered in 1993, inositol pyrophosphates are evolutionarily conserved signaling
metabolites whose versatile modes of action are being increasingly appreciated. These …

Inositol pyrophosphates are small, diffusible signaling molecules that possess the most
concentrated three‐dimensional array of phosphate groups in Nature; up to eight …

Inositol pyrophosphates (IPPs) are present in organisms ranging from plants, slime moulds
and fungi to mammals. Distinct classes of kinases generate different forms of energetic …

Obesity and obesity-induced metabolic dysfunctions are significant risk factors for
nonalcoholic fatty liver disease and cardiovascular diseases. Thus, obesity is an economic …

The inositol pyrophosphates 5-InsP7 (diphosphoinositol pentakisphosphate) and 1, 5-InsP8
(bis-diphosphoinositol tetrakisphosphate) are highly energetic cellular signals …

Inositol pyrophosphates (PP-IPs) such as 5-diphosphoinositol pentakisphosphate (5-IP7)
are inositol metabolites containing high-energy phosphoanhydride bonds. Biosynthesis of …