Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and
important biological functions. They are critical to maintain the transcriptome through post …

RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …

Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant
mortality. More than 90% cases of SMA result from deletions or mutations of Survival Motor …

Most eukaryotic genes express alternative polyadenylation (APA) isoforms with different 3′
UTR lengths, production of which is influenced by cellular conditions. Here, we show that …

Germinal centers (GCs) are essential for the establishment of long-lasting antibody
responses. GC B cells rely on post-transcriptional RNA mechanisms to translate activation …

Genome integrity must be tightly preserved to ensure cellular survival and to deter the
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …

Fighting external pathogens requires an ever-changing immune system that relies on tight
regulation of gene expression. Transcriptional control is the first step to build efficient …

Amyotrophic lateral sclerosis (ALS) is a rapidly disabling and fatal neurodegenerative
disease. Due to insufficient disease-modifying treatments, there is an unmet and urgent …