Emerging challenges and opportunities in pharmaceutical manufacturing and distribution

M Sarkis, A Bernardi, N Shah, MM Papathanasiou - Processes, 2021 - mdpi.com
The rise of personalised and highly complex drug product profiles necessitates significant
advancements in pharmaceutical manufacturing and distribution. Efforts to develop more …

Decision support tools for next-generation vaccines and advanced therapy medicinal products: present and future

M Sarkis, A Bernardi, N Shah… - Current Opinion in …, 2021 - Elsevier
Advanced Therapy Medicinal Products (ATMPs) are a novel class of biological therapeutics
that utilise ground-breaking clinical interventions to prevent and treat life-threatening …

An agent-based model for cost-effectiveness analysis in the manufacture of allogeneic human induced pluripotent cells in Japan

Y Hayashi, K Oishi, H Sugiyama - Computer Aided Chemical Engineering, 2022 - Elsevier
This work proposes an agent-based model for cost-effectiveness analysis in the
manufacture of allogeneic human induced pluripotent (hiPS) cells in Japan. The agent …

Interactive Stage-Wise Optimisation of Personalised Medicine Supply Chains

A Avramescu, M López-Ibáñez… - … Conference on the …, 2023 - Springer
Personalised medicine (PM) is a new area of healthcare that has shown promising results in
offering treatments for rare and advanced stage diseases. Nonetheless, their supply chain …

Managing manufacturing and delivery of personalised medicine: Current and future models

A Avramescu, R Allmendinger… - arXiv preprint arXiv …, 2021 - arxiv.org
With almost 50% of annual commercial drug approvals being Personalised Medicine (PM)
and its huge potential to improve quality of life, this emerging medical sector has received …

[PDF][PDF] Emerging Challenges and Opportunities in Pharmaceutical Manufacturing and Distribution. Processes 2021, 9, 457

M Sarkis, A Bernardi, N Shah, MM Papathanasiou - 2021 - psecommunity.org
The rise of personalised and highly complex drug product profiles necessitates significant
advancements in pharmaceutical manufacturing and distribution. Efforts to develop more …

[PDF][PDF] Optimization of CAR T-Cell Therapies' Supply Chain with the help of Machine Learning

S Papaiakovou - 2022 - dspace.lib.ntua.gr
Abstract Chimeric Antigen Receptor (CAR) T-cell therapies are cellular immunotherapies
that displayed encouraging results in the treatment of blood cancer types like acute …

Multiobjective Robust Optimization of Personalized Medicine Supply Chain Under Transportation Time Uncertainty

M Wan, S Liu, Y Gao, R Allmendinger… - … Conference on Intelligent …, 2023 - Springer
Currently, personalized medicine drugs have better therapeutic outcomes, but their large-
scale delivery remains a challenge. With the changing social environment, supply chain …

[PDF][PDF] Towards a holistic supply chain model for personalised medicine

A Avramescu, R Allmendinger… - 18th IEEE International …, 2021 - researchgate.net
Personalised medicine (PM) refers to treatment plans tailored for specific sub-populations
and individuals by considering environmental, genetic, and social factors. The PM field has …