Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …

As a non-invasive imaging monitoring method, molecular imaging can provide the location
and expression level of disease signature biomolecules in vivo, leading to early diagnosis of …

Repair and functional reconstruction of large jawbone defects remain one of the challenges
in the field of head and neck surgery. The recent progress in tissue engineering …

Bone defects or fractures generally heal in the absence of major interventions due to the
high regenerative capacity of bone tissue. However, in situations of severe/large bone …

Cleft alveolus, a common birth defect of the maxillary bone, affects one in 700 live births
every year. This defect is traditionally restored by autogenous bone grafts or allografts …

Mesenchymal stromal cells (MSCs) are cells with the characteristic ability of self-renewal
along with the ability to exhibit multilineage differentiation. Bone marrow (BM) is the first …

Increased multiantibiotic-resistant bacteria means that infected bone defects remain a
significant challenge to clinics. Great interest has emerged in the use of non-antibiotic …

Lack of bone volume to place dental implants is frequently a problem in the reconstruction of
edentulous patients. Even though autografts are the gold standard for jaw regeneration …

Introdução: A área da medicina que utiliza de células para realização de procedimentos
terapêuticos de correção estrutural no organismo é a terapia celular. Objetivo: investigar as …