The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

The rapid emergence of drug resistance continues to outpace the development of new
antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited …

Silicon-based materials and their oxides are widely used in drug delivery, dietary
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …

The application of mesoporous silica nanoparticles (MSNs) as drug delivery systems to
deliver drugs, proteins, and genes has expanded considerably in recent years, using in vitro …

Gelatin is a biocompatible, biodegradable, cheap, and nontoxic material, which is already
used for pharmaceutical applications. Nanoparticles from gelatin (GNPs) are considered a …

Most nanomedicines require efficient in vivo delivery to elicit meaningful diagnostic and
therapeutic effects. However, en route to their intended tissues, systemically administered …

Abstract Aluminium (Al) oxyhydroxide (Alhydrogel®), the main adjuvant licensed for human
and animal vaccines, consists of primary nanoparticles that spontaneously agglomerate …

Nanosafety assessment has experienced an intense era of research during the past
decades driven by a vivid interest of regulators, industry, and society. Toxicological assays …

This study comprehensively investigates the changing biodistribution of fluorescent-labelled
polystyrene latex bead nanoparticles in a mouse model of inflammation. Since inflammation …

The goal of this study was to develop and characterize a novel intravaginal film platform for
targeted delivery of small interfering RNA (siRNA)-loaded nanoparticles (NP) to dendritic …