The corticotropin-releasing factor family: physiology of the stress response

JM Deussing, A Chen - Physiological reviews, 2018 - journals.physiology.org
The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

[HTML][HTML] Stress modulation of opposing circuits in the bed nucleus of the stria terminalis

SE Daniel, DG Rainnie - Neuropsychopharmacology, 2016 - nature.com
The anterior bed nucleus of the stria terminalis (BNST) has been recognized as a critical
structure in regulating trait anxiety, contextual fear memory, and appetitive behavior, and is …

Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria …

J Dabrowska, R Hazra, TH Ahern, JD Guo… - …, 2011 - Elsevier
Activation of corticotrophin releasing factor (CRF) neurons in the paraventricular nucleus of
the hypothalamus (PVN) is necessary for establishing the classic endocrine response to …

The CRF family of neuropeptides and their receptors-mediators of the central stress response

N Dedic, A Chen, JM Deussing - Current molecular …, 2018 - ingentaconnect.com
Background: Dysregulated stress neurocircuits, caused by genetic and/or environmental
changes, underlie the development of many neuropsychiatric disorders. Corticotropin …

[HTML][HTML] Central CRF neurons are not created equal: phenotypic differences in CRF-containing neurons of the rat paraventricular hypothalamus and the bed nucleus …

J Dabrowska, R Hazra, JD Guo, S DeWitt… - Frontiers in …, 2013 - frontiersin.org
Corticotrophin-releasing factor (CRF) plays a key role in initiating many of the endocrine,
autonomic, and behavioral responses to stress. CRF-containing neurons of the …

[HTML][HTML] Characterization of Corticotropin-Releasing Hormone neurons in the Paraventricular Nucleus of the Hypothalamus of Crh-IRES-Cre Mutant Mice

JI Wamsteeker Cusulin, T Füzesi, AG Watts, JS Bains - PLoS One, 2013 - journals.plos.org
Corticotropin-releasing hormone (CRH)-containing neurons in the paraventricular nucleus
of the hypothalamus (PVN) initiate and control neuroendocrine responses to psychogenic …

[HTML][HTML] A transgenic rat for investigating the anatomy and function of corticotrophin releasing factor circuits

MB Pomrenze, EZ Millan, FW Hopf, R Keiflin… - Frontiers in …, 2015 - frontiersin.org
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates
adaptive responses to stress. CRF projections from neurons in the central nucleus of the …

The intersection of stress and reward: BNST modulation of aversive and appetitive states

S Ch'ng, J Fu, RM Brown, SJ McDougall… - Progress in Neuro …, 2018 - Elsevier
The bed nucleus of the stria terminalis (BNST) is widely acknowledged as a brain structure
that regulates stress and anxiety states, as well as aversive and appetitive behaviours. The …

Diversity of reporter expression patterns in transgenic mouse lines targeting corticotropin-releasing hormone-expressing neurons

Y Chen, J Molet, BG Gunn, K Ressler… - Endocrinology, 2015 - academic.oup.com
Transgenic mice, including lines targeting corticotropin-releasing factor (CRF or CRH), have
been extensively employed to study stress neurobiology. These powerful tools are poised to …

Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety

KS Sink, DL Walker, SM Freeman, EI Flandreau… - Molecular …, 2013 - nature.com
The lateral division of the bed nucleus of the stria terminalis (BNST), which forms part of the
circuitry regulating fear and anxiety, contains a large number of neurons expressing …