[HTML][HTML] Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy

X Li, AL Corbett, E Taatizadeh, N Tasnim, JP Little… - APL …, 2019 - pubs.aip.org
ABSTRACT Exosomes are small ($30–140 nm) lipid bilayer-enclosed particles of
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …

Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds

AA Farooqi, NN Desai, MZ Qureshi… - Biotechnology …, 2018 - Elsevier
A rapidly growing body of experimental evidence has begun to shed light on the wide
ranging molecular mechanisms which modulate intra-and inter-cellular communications. A …

[HTML][HTML] A review on drug delivery system for tumor therapy

G Liu, L Yang, G Chen, F Xu, F Yang, H Yu… - Frontiers in …, 2021 - frontiersin.org
In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

[HTML][HTML] Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong, LS Steelman… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design

SAA Kooijmans, OG de Jong, RM Schiffelers - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …

[HTML][HTML] Curcumin as prospective anti-aging natural compound: focus on brain

T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …

Curcumin encapsulated in milk exosomes resists human digestion and possesses enhanced intestinal permeability in vitro

M Vashisht, P Rani, SK Onteru, D Singh - Applied Biochemistry and …, 2017 - Springer
Exosomes, the extracellular secretary nano-vesicles, act as carriers of biomolecules to the
target cells. They exhibit several attributes of an efficient drug delivery system. Curcumin …

[HTML][HTML] Exosomes with low miR-34c-3p expression promote invasion and migration of non-small cell lung cancer by upregulating integrin α2β1

W Huang, Y Yan, Y Liu, M Lin, J Ma, W Zhang… - Signal transduction and …, 2020 - nature.com
Exosomes play critical roles in regulating various physiological and pathological processes,
including immune stimulation, immune suppression, cardiovascular diseases, and cancers …

[HTML][HTML] Tumor cells derived-exosomes as angiogenenic agents: possible therapeutic implications

M Ahmadi, J Rezaie - Journal of translational medicine, 2020 - Springer
Angiogenesis is a multistep process and various molecules are involved in regulating it.
Extracellular vesicles are cell-derived particles, secreted from several types of cells and are …

[HTML][HTML] Mass spectrometry-based proteome profiling of extracellular vesicles and their roles in cancer biology

R Bandu, JW Oh, KP Kim - Experimental & molecular medicine, 2019 - nature.com
Over the past three decades, extracellular vesicles (EVs) have arisen as important mediators
of intercellular communication that are involved in the transmission of biological signals …