Asymmetric organocatalysis: an enabling technology for medicinal chemistry
B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles
Y Wang, AA Cobo, AK Franz - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Asymmetric catalytic multicomponent cascade reactions have become indispensable tools
for enantioselective construction of spirooxindoles. In recent years, a number of successful …
for enantioselective construction of spirooxindoles. In recent years, a number of successful …
Challenges and opportunities in multicatalysis
Multicatalysis is an emerging field targeting the development of efficient catalytic
transformations to quickly convert relatively simple starting materials into more complex …
transformations to quickly convert relatively simple starting materials into more complex …
Visible light organic photoredox catalytic cascade reactions
GQ Xu, PF Xu - Chemical Communications, 2021 - pubs.rsc.org
Over the past years, impressive progress has been made in the development of organic
photoredox catalytic cascade reactions without the participation of expensive and toxic …
photoredox catalytic cascade reactions without the participation of expensive and toxic …
Photo‐biocatalytic cascades: combining chemical and enzymatic transformations fueled by light
In the field of green chemistry, light–an attractive natural agent–has received particular
attention for driving biocatalytic reactions. Moreover, the implementation of light to drive …
attention for driving biocatalytic reactions. Moreover, the implementation of light to drive …
Recent developments in next generation (S)-proline-derived chiral organocatalysts
E Juaristi - Tetrahedron, 2021 - Elsevier
In the area of asymmetric organocatalysis, significant effort has been dedicated during the
last decade to improve the performance of emblematic catalysts such as proline, as well as …
last decade to improve the performance of emblematic catalysts such as proline, as well as …
Revealing the similarities of α, β‐unsaturated iminiums and acylazoliums in organocatalysis
The secondary amine‐catalyzed reactions proceeding via α, β‐unsaturated iminiums and
the N‐heterocyclic carbene (NHC)‐catalyzed transformations taking place via α, β …
the N‐heterocyclic carbene (NHC)‐catalyzed transformations taking place via α, β …
[HTML][HTML] Recent developments in one-pot stepwise synthesis (OPSS) of small molecules
X Ma, W Zhang - Iscience, 2022 - cell.com
One-pot synthesis is an active topic in organic chemistry due to its intrinsic advantages of
simple operation, high mass efficiency, low cost, and less amount of waste disposal. Among …
simple operation, high mass efficiency, low cost, and less amount of waste disposal. Among …
[HTML][HTML] Iodonium salts as efficient iodine (III)-based noncovalent organocatalysts for Knorr-type reactions
SN Yunusova, AS Novikov, NS Soldatova, MA Vovk… - RSC …, 2021 - pubs.rsc.org
Hypervalent iodine (III)-derivatives display higher catalytic activity than other aliphatic and
aromatic iodine (I)–or bromine (I)-containing substrates for a Knorr-type reaction of N-acetyl …
aromatic iodine (I)–or bromine (I)-containing substrates for a Knorr-type reaction of N-acetyl …
[HTML][HTML] Chiral thioureas—preparation and significance in asymmetric synthesis and medicinal chemistry
F Steppeler, D Iwan, E Wojaczyńska, J Wojaczyński - Molecules, 2020 - mdpi.com
For almost 20 years, thioureas have been experiencing a renaissance of interest with the
emerged development of asymmetric organocatalysts. Due to their relatively high acidity and …
emerged development of asymmetric organocatalysts. Due to their relatively high acidity and …