Advances in the microbial etiology and pathogenesis of early childhood caries

E Hajishengallis, Y Parsaei, MI Klein… - Molecular oral …, 2017 - Wiley Online Library
Early childhood caries (ECC) is one of the most prevalent infectious diseases affecting
children worldwide. ECC is an aggressive form of dental caries, which, left untreated, can …

[HTML][HTML] Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms

MI Klein, G Hwang, PHS Santos… - Frontiers in cellular …, 2015 - frontiersin.org
Biofilms are highly structured microbial communities that are enmeshed in a self-produced
extracellular matrix. Within the complex oral microbiome, Streptococcus mutans is a major …

[HTML][HTML] Glycan recognition at the saliva–oral microbiome interface

BW Cross, S Ruhl - Cellular immunology, 2018 - Elsevier
The mouth is a first critical interface where most potentially harmful substances or pathogens
contact the host environment. Adaptive and innate immune defense mechanisms are …

Dental caries: A review

NJ Veiga, D Aires, F Douglas, M Pereira… - Journal of dental and …, 2016 - repositorio.ucp.pt
ntroduction: Dental caries is the most prevalent chronic disease worldwide. It's an infectious
disease characterized by a multifactorial etiology and slow evolution that leads to the …

Extracellular DNA and lipoteichoic acids interact with exopolysaccharides in the extracellular matrix of Streptococcus mutans biofilms

MC Castillo Pedraza, TF Novais, RC Faustoferri… - Biofouling, 2017 - Taylor & Francis
Streptococcus mutans-derived exopolysaccharides are virulence determinants in the matrix
of biofilms that cause caries. Extracellular DNA (eDNA) and lipoteichoic acid (LTA) are found …

[HTML][HTML] Antibacterial properties in vitro of magnesium oxide nanoparticles for dental applications

AP Rodríguez-Hernández, AL Vega-Jiménez… - Nanomaterials, 2023 - mdpi.com
(1) Dental caries, periodontitis, or peri-implantitis are commensal infections related to oral
biofilm former bacteria. Likewise, magnesium oxide nanoparticles (MgO-NPs) were studied …

Inhibition of Streptococcus mutans biofilm formation using extracts from Assam tea compared to green tea

T Kawarai, N Narisawa, S Yoneda, Y Tsutsumi… - Archives of oral …, 2016 - Elsevier
Objective Streptococcus mutans, a gram-positive oral bacterium, has been identified as one
of the principal etiological agents of human dental caries. To clarify the nature of the …

[HTML][HTML] Effect of tt-farnesol and myricetin on in vitro biofilm formed by Streptococcus mutans and Candida albicans

GR Rocha, EJ Florez Salamanca, AL de Barros… - … and alternative medicine, 2018 - Springer
Background Dental caries is considered a multifactorial disease, in which microorganisms
play an important role. The diet is decisive in the biofilm formation because it provides the …

Prenatal maternal factors, intergenerational transmission of disease, and child oral health outcomes

TL Finlayson, A Gupta, FJ Ramos-Gomez - Dental Clinics, 2017 - dental.theclinics.com
Method Prenatal and postdelivery maternal interventions (1998–2016) that focused on
reduction of intergenerational MS transmission, child MS, and infant caries were reviewed …

Nanoparticle carrier co-delivery of complementary antibiofilm drugs abrogates dual species cariogenic biofilm formation in vitro

G Roncari Rocha, KR Sims Jr, B Xiao… - Journal of oral …, 2022 - Taylor & Francis
Background Dental caries is a multifactorial disease caused by pathogenic biofilm. In
particular, Streptococcus mutans synthesizes biofilm exopolysaccharides, while Candida …