This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

The calcium signal is a powerful and multifaceted tool by which cells can achieve specific
outcomes. Cellular machinery important in tumour progression is often driven or influenced …

The intracellular calcium ions (Ca 2+) act as second messenger to regulate gene
transcription, cell proliferation, migration and death. Accumulating evidences have …

It is the nature of the calcium signal, as determined by the coordinated activity of a suite of
calcium channels, pumps, exchangers and binding proteins that ultimately guides a cell's …

Potassium channels are pore-forming transmembrane proteins that regulate a multitude of
biological processes by controlling potassium flow across cell membranes. Aberrant …

The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH)
in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated …

Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary
sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are …

Cancer cells secrete copious amounts of exosomes, and elevated intracellular Ca 2+ is
critical for tumor progression and metastasis, but the underlying cellular mechanisms are …

Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

Signals from the tumor microenvironment trigger cancer cells to adopt an invasive
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …