A guide to plasma membrane solute carrier proteins
MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …
of transporter proteins and their roles in human cells. The SLC superfamily currently …
The calcium–cancer signalling nexus
GR Monteith, N Prevarskaya… - Nature Reviews …, 2017 - nature.com
The calcium signal is a powerful and multifaceted tool by which cells can achieve specific
outcomes. Cellular machinery important in tumour progression is often driven or influenced …
outcomes. Cellular machinery important in tumour progression is often driven or influenced …
[HTML][HTML] Targeting calcium signaling in cancer therapy
C Cui, R Merritt, L Fu, Z Pan - Acta pharmaceutica sinica B, 2017 - Elsevier
The intracellular calcium ions (Ca 2+) act as second messenger to regulate gene
transcription, cell proliferation, migration and death. Accumulating evidences have …
transcription, cell proliferation, migration and death. Accumulating evidences have …
[HTML][HTML] Altered calcium signaling in cancer cells
TA Stewart, KTDS Yapa, GR Monteith - Biochimica et Biophysica Acta (BBA …, 2015 - Elsevier
It is the nature of the calcium signal, as determined by the coordinated activity of a suite of
calcium channels, pumps, exchangers and binding proteins that ultimately guides a cell's …
calcium channels, pumps, exchangers and binding proteins that ultimately guides a cell's …
[HTML][HTML] Targeting potassium channels in cancer
X Huang, LY Jan - The Journal of cell biology, 2014 - ncbi.nlm.nih.gov
Potassium channels are pore-forming transmembrane proteins that regulate a multitude of
biological processes by controlling potassium flow across cell membranes. Aberrant …
biological processes by controlling potassium flow across cell membranes. Aberrant …
Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling
The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH)
in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated …
in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated …
[HTML][HTML] Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene
Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary
sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are …
sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are …
[HTML][HTML] A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4
SW Messenger, SS Woo, Z Sun… - The Journal of cell …, 2018 - ncbi.nlm.nih.gov
Cancer cells secrete copious amounts of exosomes, and elevated intracellular Ca 2+ is
critical for tumor progression and metastasis, but the underlying cellular mechanisms are …
critical for tumor progression and metastasis, but the underlying cellular mechanisms are …
[HTML][HTML] The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer
MW Berchtold, A Villalobo - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Signals from the tumor microenvironment trigger cancer cells to adopt an invasive
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …
phenotype through epithelial–mesenchymal transition (EMT). Relatively little is known …