For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Severe Sepsis and Septic Shock | New England Journal of Medicine Skip to main content The
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Objectives: Trends in severe sepsis mortality derived from administrative data may be
biased by changing International Classification of Diseases, 9th Revision, Clinical …

Objective To demonstrate the incremental benefit of using free text data in addition to vital
sign and demographic data to identify patients with suspected infection in the emergency …

Objectives Sepsis guidelines recommend obtaining blood cultures before starting anti-
infective therapy in patients with sepsis. However, little is known of how antibiotic treatment …

Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Abstract Objective The Surviving Sepsis Campaign (SSC or “the Campaign”) developed
guidelines for management of severe sepsis and septic shock. A performance improvement …

Context Goal-directed resuscitation for severe sepsis and septic shock has been reported to
reduce mortality when applied in the emergency department. Objective To test the …

Background Severe sepsis is common and often fatal. The expanding armamentarium of
evidence-based therapies has improved the outcomes of persons with this disease …

Objectives To ascertain the absolute number of M edicare beneficiaries surviving at least 3
years after severe sepsis and to estimate their burden of cognitive dysfunction and disability …